Reactome | (BPDE-G:C)-DNA Template [nucleoplasm]

(BPDE-G:C)-DNA Template [nucleoplasm]

Stable Identifier

R-HSA-5655915

Type

Genes and Transcripts [GenomeEncodedEntity]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

DNA template with benzo(a)pyrene diol epoxide guanine adduct paired with cytosine

Locations in the PathwayBrowser

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DNA Repair (Homo sapiens)

- DNA Damage Bypass (Homo sapiens)
  - Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template (Homo sapiens)
    - Translesion synthesis by POLK (Homo sapiens)
      - POLK and POLZ cooperate in elongation of mispaired primer termini (Homo sapiens)
        
        POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
        
        MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
        
        (Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
        
        (BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
      - POLK incorporates dNMP opposite to damaged DNA base (Homo sapiens)
        
        POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
        
        MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
        
        (Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
        
        (BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)

Participates

as a member of

(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)

Cross References

ChEBI

16991

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