RCHY1 binds POLH

Stable Identifier
R-HSA-5655142
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
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RCHY1 binds POLH
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RCHY1 (Pirh2) is an E3 ubiquitin ligase that binds DNA polymerase eta (POLH). This interaction involves the polymerase-associated domain of POLH and the RING finger of RCHY1 (Jung et al. 2010).

Literature References
PubMed ID Title Journal Year
20008555 Pirh2 E3 ubiquitin ligase targets DNA polymerase eta for 20S proteasomal degradation

Jung, YS, Liu, G, Chen, X

Mol. Cell. Biol. 2010
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Orthologous Events
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RCHY1 binds POLH (Sus scrofa)
Authored
Orlic-Milacic, M  (2014-12-11)
Reviewed
Borowiec, JA  (2015-01-07)
Created
Orlic-Milacic, M  (2014-12-04)
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