FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3

Stable Identifier
R-HSA-5654709
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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Once recruited to the membrane, PI3K catalyzes the phosphorylation of PI(4,5)P2 to PI(3,4,5)P3.

Participants
Participates
Catalyst Activity

phosphatidylinositol-4,5-bisphosphate 3-kinase activity of Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane]

Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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