SLC2A1 tetramer transports Glc from cytosol to Golgi lumen

Stable Identifier
R-HSA-5653873
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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SLC2A1 (aka GLUT1) tetramer in the Golgi membrane mediates the facilitated diffusion of glucose from the cytosol into the Golgi lumen. SLC2A1, normally confined to the plasma membrane, is also abundant in the Golgi membranes of epithelial cells of the lactating mammary gland, as demonstrated experimentally in mice (Nemeth et al. 2000). It is not known how this physiological state-specific relocalization is regulated.

Literature References
PubMed ID Title Journal Year
10759149 Golgi targeting of the GLUT1 glucose transporter in lactating mouse mammary gland

Nemeth, BA, Tsang, SW, Geske, RS, Haney, PM

Pediatr. Res. 2000
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
glucose transmembrane transporter activity of SLC2A1 tetramer [Golgi membrane]
Physical Entity
Activity
Orthologous Events
Reviewed
Created