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PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template
Stable Identifier
R-HSA-5653837
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
DNA Repair (Homo sapiens)
DNA Damage Bypass (Homo sapiens)
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template (Homo sapiens)
Termination of translesion DNA synthesis (Homo sapiens)
POLD,POLE binds deISGylated PCNA after TLS (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
POLD,POLE complete replication of damaged DNA after TLS (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
24768535
Modification of PCNA by ISG15 plays a crucial role in termination of error-prone translesion DNA synthesis
Mol. Cell
2014
Participants
components
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
POLD,POLE [nucleoplasm] (Homo sapiens)
Participant Of
input
POLD,POLE complete replication of damaged DNA after TLS
output
POLD,POLE binds deISGylated PCNA after TLS
Inferred To
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Arabidopsis thaliana)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Bos taurus)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Canis familiaris)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Danio rerio)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Drosophila melanogaster)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Gallus gallus)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Mus musculus)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Oryza sativa)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Rattus norvegicus)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Saccharomyces cerevisiae)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Sus scrofa)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Taeniopygia guttata)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Xenopus tropicalis)
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