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LAMTOR3 [lysosomal membrane]
Stable Identifier
R-HSA-5653581
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal membrane
Synonyms
Ragulator complex protein LAMTOR3, LTOR3_HUMAN
Icon
Locations in the PathwayBrowser for interactor UniProt:Q9GZT8 NIF3L
Expand all
Signal Transduction (Homo sapiens)
mTOR signalling (Homo sapiens)
Formation of Ragulator complex (Homo sapiens)
LAMTOR3 [lysosomal membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UHA4 LAMTOR3
Gene Names
LAMTOR3, MAP2K1IP1, MAPKSP1, PRO2783
Chain
chain:1-124
Reference Genes
BioGPS Gene:8649 LAMTOR3
COSMIC (genes):LAMTOR3 LAMTOR3
CTD Gene:8649 LAMTOR3
dbSNP Gene:8649 LAMTOR3
ENSEMBL:ENSG00000109270 LAMTOR3
HGNC:15606 LAMTOR3
KEGG Gene (Homo sapiens):8649 LAMTOR3
Monarch:8649 LAMTOR3
NCBI Gene:8649 LAMTOR3
OMIM:603296 LAMTOR3
UCSC:Q9UHA4 LAMTOR3
Reference Transcript
RefSeq:NM_021970.3 LAMTOR3
RefSeq:NM_001243736.1 LAMTOR3
Other Identifiers
0000110338
11718768_a_at
11718769_a_at
16978301
1SKO
217971_at
227562_at
26858
2779398
2779399
2779400
2779409
2779410
2779411
2779412
2779413
2779414
2779415
2779418
2779421
2779423
2779424
2779425
2779427
2872528
2ZL1
3CPT
46103_at
46221_i_at
46222_r_at
5X6U
5X6V
5Y39
5Y3A
6B9X
6EHP
6EHR
8101925
8649
A_23_P110362
A_32_P10311
A_33_P3251480
AAF17239
AAG35540
AAH26245
AF130115
AF201947
AK311755
AL544981
AP001962
BAG34698
BC026245
CCDS3652
CCDS58920
CH471057
EAX06112
ENSG00000109270
ENSP00000226522
ENSP00000424183
ENST00000226522
ENST00000226522.8
ENST00000499666
ENST00000499666.6
EntrezGene:8649
EntrezGene:LAMTOR3
g11496276_3p_at
GE80264
GE87054
GO:0000165
GO:0000186
GO:0002376
GO:0003674
GO:0005085
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005623
GO:0005737
GO:0005764
GO:0005765
GO:0005768
GO:0005770
GO:0005773
GO:0005886
GO:0005925
GO:0006464
GO:0006810
GO:0006914
GO:0007049
GO:0007050
GO:0007165
GO:0008150
GO:0009056
GO:0010008
GO:0016020
GO:0016192
GO:0016241
GO:0019209
GO:0019899
GO:0030234
GO:0031410
GO:0031902
GO:0032006
GO:0032008
GO:0032991
GO:0034613
GO:0035579
GO:0043226
GO:0043312
GO:0060090
GO:0070062
GO:0070821
GO:0071230
GO:0071986
HGNC:15606
HPA026858
Hs.332556.0.S1_3p_at
ILMN_1659415
ILMN_3225432
ILMN_3274246
ILMN_3301197
IPR015019
LAMTOR3
LAMTOR3-201
LAMTOR3-202
MIM:603296
NM_001243736
NM_021970
NP_001230665
NP_068805
PF08923
PH_hs_0030174
PH_hs_0037100
SM01278
TC04001416.hg
TC04002643.hg
UPI000012F194
UPI0000422AC6
Participant Of
input
Formation of Ragulator complex
hasComponent
Ragulator [lysosomal membrane]
Other forms of this molecule
LAMTOR3 [tertiary granule membrane]
LAMTOR3 [plasma membrane]
LAMTOR3 [specific granule membrane]
LAMTOR3 [endosome membrane]
Inferred To
Ghost homologue of LAMTOR3 [lysosomal membrane] (Saccharomyces cerevisiae)
Ghost homologue of LAMTOR3 [lysosomal membrane] (Schizosaccharomyces pombe)
LAMTOR3 [lysosomal membrane] (Bos taurus)
LAMTOR3 [lysosomal membrane] (Caenorhabditis elegans)
LAMTOR3 [lysosomal membrane] (Canis familiaris)
LAMTOR3 [lysosomal membrane] (Danio rerio)
LAMTOR3 [lysosomal membrane] (Dictyostelium discoideum)
LAMTOR3 [lysosomal membrane] (Drosophila melanogaster)
LAMTOR3 [lysosomal membrane] (Gallus gallus)
LAMTOR3 [lysosomal membrane] (Mus musculus)
LAMTOR3 [lysosomal membrane] (Rattus norvegicus)
LAMTOR3 [lysosomal membrane] (Sus scrofa)
LAMTOR3 [lysosomal membrane] (Xenopus tropicalis)
Cross References
RefSeq
NP_001230665.1
,
NP_068805.1
OpenTargets
ENSG00000109270
GeneCards
Q9UHA4
PRO
Q9UHA4
PDB
5Y39
,
1SKO
,
6B9X
,
5Y3A
,
3CPT
,
2ZL1
,
6EHP
,
5X6V
,
5X6U
,
6EHR
Interactors (14)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Y2Q5 LAMTOR2
5
LAMTOR2 [plasma membrane]
(R-HSA-6806286)
LAMTOR2 [tertiary granule membrane]
(R-HSA-6800165)
LAMTOR2 [specific granule membrane]
(R-HSA-6800168)
LAMTOR2 [endosome membrane]
(R-HSA-5693293)
LAMTOR2 [lysosomal membrane]
(R-HSA-5653583)
0.935
17
UniProt:Q9HB90 RRAGC
1
RRAGC [cytosol]
(R-HSA-5653949)
0.643
8
UniProt:Q5VZM2 RRAGB
1
RRAGB [cytosol]
(R-HSA-5653579)
0.643
5
UniProt:Q6IAA8 LAMTOR1
5
LAMTOR1 [azurophil granule membrane]
(R-HSA-6799633)
LAMTOR1 [ficolin-1-rich granule membrane]
(R-HSA-6801003)
LAMTOR1 [plasma membrane]
(R-HSA-6806270)
LAMTOR1 [specific granule membrane]
(R-HSA-6799631)
LAMTOR1 [lysosomal membrane]
(R-HSA-5653582)
0.597
5
UniProt:Q9GZT8 NIF3L
0.556
3
UniProt:Q0VGL1 LAMTOR4
1
LAMTOR4 [lysosomal membrane]
(R-HSA-5655432)
0.527
3
UniProt:Q9NQL2 RRAGD
1
RRAGD [cytosol]
(R-HSA-5653953)
0.527
2
UniProt:O43504 LAMTOR5
1
LAMTOR5 [lysosomal membrane]
(R-HSA-5655441)
0.527
3
UniProt:Q8NBW4 SLC38A9
1
SLC38A9 [lysosomal membrane]
(R-HSA-5215938)
0.499
5
UniProt:Q8NAM6 ZSCA4
0.488
2
UniProt:Q9BWW8 APOL6
0.488
2
UniProt:P19532 TFE3
0.488
2
UniProt:Q49A26-4 GLYR1
0.488
2
UniProt:Q96PF1 TGM7
0.488
2
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