LIG1 and POLB dissociate from repaired dsDNA

Stable Identifier
R-HSA-5651792
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
nucleoplasm
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LIG1 and POLB dissociate from repaired dsDNA
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After the POLB-dependent long patch base excision (BER) is completed, POLB and LIG1 dissociate from repaired DNA (Ranalli et al. 2002).

Literature References
PubMed ID Title Journal Year
12200445 AP endonuclease 1 coordinates flap endonuclease 1 and DNA ligase I activity in long patch base excision repair.

Ranalli, TA, Tom, S, Bambara, RA

J Biol Chem 2002
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Authored
Orlic-Milacic, M  (2014-12-04)
Reviewed
Borowiec, JA  (2014-12-22)
Created
Orlic-Milacic, M  (2014-11-24)
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