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ACSL1 gene [nucleoplasm]
Stable Identifier
R-HSA-5649949
Type
DNA Sequence [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
Epigenetic regulation by WDR5-containing histone modifying complexes (Homo sapiens)
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes (Homo sapiens)
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes (Homo sapiens)
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis (Homo sapiens)
ACSL1 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex (Homo sapiens)
ACSL1 gene [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:ACSL1 gene:H3K4me1-Nucleosomes:MLL4,(MLL3)-ASCOM [nucleoplasm] (Homo sapiens)
ACSL1 gene:H3K4me1-nucleosomes [nucleoplasm] (Homo sapiens)
ACSL1 gene [nucleoplasm] (Homo sapiens)
Coactivators are recruited to liganded PPARG:RXRA heterodimer (Homo sapiens)
Activated PPARG:RXRA:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:ACSL1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
ACSL1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
ACSL1 gene [nucleoplasm] (Homo sapiens)
PPARG ligands:PPARG:RXRA ligands:RXRA:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound PPARG:Ligand-bound RXRA:ACSL1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
ACSL1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
ACSL1 gene [nucleoplasm] (Homo sapiens)
Corepressors are released from liganded PPARG:RXRA heterodimer (Homo sapiens)
PPARG ligands:PPARG:RXRA ligands:RXRA:Corepressors:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:ACSL1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
ACSL1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
ACSL1 gene [nucleoplasm] (Homo sapiens)
PPARG ligands:PPARG:RXRA ligands:RXRA:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound PPARG:Ligand-bound RXRA:ACSL1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
ACSL1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
ACSL1 gene [nucleoplasm] (Homo sapiens)
KMT2D,(KMT2C) complex monomethylates nucleosomes at PPARG:RXRA-bound enhancers (Homo sapiens)
Activated PPARG:RXRA:adipogenesis genes:H3K4me1-Nucleosomes:MLL4,(MLL3)-ASCOM [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:ACSL1 gene:H3K4me1-Nucleosomes:MLL4,(MLL3)-ASCOM [nucleoplasm] (Homo sapiens)
ACSL1 gene:H3K4me1-nucleosomes [nucleoplasm] (Homo sapiens)
ACSL1 gene [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:adipogenesis genes:Nucleosomes:MLL4,(MLL3)-ASCOM [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:MLL4,(MLL3)-ASCOM:ACSL1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
ACSL1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
ACSL1 gene [nucleoplasm] (Homo sapiens)
MLL4-ASCOM,(MLL3-ASCOM) complex is recruited to ligand- and coactivator-bound PPARG:RXRA heterodimer (Homo sapiens)
Activated PPARG:RXRA:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:ACSL1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
ACSL1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
ACSL1 gene [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:adipogenesis genes:Nucleosomes:MLL4,(MLL3)-ASCOM [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:MLL4,(MLL3)-ASCOM:ACSL1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
ACSL1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
ACSL1 gene [nucleoplasm] (Homo sapiens)
PPARG binds ligands (Homo sapiens)
PPARG ligands:PPARG:RXRA:Corepressors:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound PPARG:RXRA:NCoR/SMRT:ACSL1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
ACSL1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
ACSL1 gene [nucleoplasm] (Homo sapiens)
PPARG:RXRA:NCoR/SMRT:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
PPARG:RXRA:NCoR/SMRT:ACSL1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
ACSL1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
ACSL1 gene [nucleoplasm] (Homo sapiens)
PPARG:RXRA heterodimer binds target gene loci (Homo sapiens)
Adipogenesis target genes of PPARG and MLL3/4:Nucleosomes [nucleoplasm] (Homo sapiens)
ACSL1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
ACSL1 gene [nucleoplasm] (Homo sapiens)
PPARG:RXRA:Adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
PPARG:RXRA:ACSL1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
ACSL1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
ACSL1 gene [nucleoplasm] (Homo sapiens)
RXRA binds ligands (Homo sapiens)
PPARG ligands:PPARG:RXRA ligands:RXRA:Corepressors:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:ACSL1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
ACSL1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
ACSL1 gene [nucleoplasm] (Homo sapiens)
PPARG ligands:PPARG:RXRA:Corepressors:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound PPARG:RXRA:NCoR/SMRT:ACSL1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
ACSL1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
ACSL1 gene [nucleoplasm] (Homo sapiens)
Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci (Homo sapiens)
PPARG:RXRA:Adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
PPARG:RXRA:ACSL1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
ACSL1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
ACSL1 gene [nucleoplasm] (Homo sapiens)
PPARG:RXRA:NCoR/SMRT:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
PPARG:RXRA:NCoR/SMRT:ACSL1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
ACSL1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
ACSL1 gene [nucleoplasm] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Regulation of lipid metabolism by PPARalpha (Homo sapiens)
PPARA activates gene expression (Homo sapiens)
Expression of ACSL1 (Homo sapiens)
ACSL1 gene [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
ENSEMBL:ENSG00000151726 ACSL1
Gene Names
ACSL1, FACL1, FACL2, LACS, LACS1, LACS2
Participates
as an input of
Expression of ACSL1 (Homo sapiens)
ACSL1 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex (Homo sapiens)
as a component of
ACSL1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
ACSL1 gene:H3K4me1-nucleosomes [nucleoplasm] (Homo sapiens)
Inferred To
Ghost homologue of ACSL1 gene [nucleoplasm]
(Bos taurus)
Ghost homologue of ACSL1 gene [nucleoplasm]
(Caenorhabditis elegans)
Ghost homologue of ACSL1 gene [nucleoplasm]
(Canis familiaris)
Ghost homologue of ACSL1 gene [nucleoplasm]
(Danio rerio)
Ghost homologue of ACSL1 gene [nucleoplasm]
(Drosophila melanogaster)
Ghost homologue of ACSL1 gene [nucleoplasm]
(Gallus gallus)
Ghost homologue of ACSL1 gene [nucleoplasm]
(Mus musculus)
Ghost homologue of ACSL1 gene [nucleoplasm]
(Rattus norvegicus)
Ghost homologue of ACSL1 gene [nucleoplasm]
(Sus scrofa)
Ghost homologue of ACSL1 gene [nucleoplasm]
(Xenopus tropicalis)
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