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SSB(3'Pi)-gap-dsDNA [nucleoplasm]
Stable Identifier
R-HSA-5649821
Type
Genes and Transcripts [GenomeEncodedEntity]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
DNA Repair (Homo sapiens)
Base Excision Repair (Homo sapiens)
Resolution of Abasic Sites (AP sites) (Homo sapiens)
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway (Homo sapiens)
LIG3:XRCC1 and PNKP bind NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA (Homo sapiens)
NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:SSB(3'Pi)-gap-dsDNA [nucleoplasm] (Homo sapiens)
NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA [nucleoplasm] (Homo sapiens)
SSB(3'Pi)-gap-dsDNA [nucleoplasm] (Homo sapiens)
NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA [nucleoplasm] (Homo sapiens)
SSB(3'Pi)-gap-dsDNA [nucleoplasm] (Homo sapiens)
PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) (Homo sapiens)
NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:SSB(3'Pi)-gap-dsDNA [nucleoplasm] (Homo sapiens)
NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA [nucleoplasm] (Homo sapiens)
SSB(3'Pi)-gap-dsDNA [nucleoplasm] (Homo sapiens)
POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) (Homo sapiens)
NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA [nucleoplasm] (Homo sapiens)
SSB(3'Pi)-gap-dsDNA [nucleoplasm] (Homo sapiens)
Participates
as a component of
NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA [nucleoplasm] (Homo sapiens)
Inferred To
Ghost homologue of SSB(3'Pi)-gap-dsDNA [nucleoplasm]
(Canis familiaris)
Ghost homologue of SSB(3'Pi)-gap-dsDNA [nucleoplasm]
(Danio rerio)
Ghost homologue of SSB(3'Pi)-gap-dsDNA [nucleoplasm]
(Dictyostelium discoideum)
Ghost homologue of SSB(3'Pi)-gap-dsDNA [nucleoplasm]
(Mus musculus)
Ghost homologue of SSB(3'Pi)-gap-dsDNA [nucleoplasm]
(Rattus norvegicus)
Ghost homologue of SSB(3'Pi)-gap-dsDNA [nucleoplasm]
(Sus scrofa)
Ghost homologue of SSB(3'Pi)-gap-dsDNA [nucleoplasm]
(Xenopus tropicalis)
Cross References
ChEBI
16991
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