LIG3:XRCC1, POLB, NEIL1,NEIL2 and PNKP dissociate from the BER site

Stable Identifier
R-HSA-5649724
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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LIG3:XRCC1, POLB, NEIL1,NEIL2 and PNKP dissociate from the BER site
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After the completion of the base excision repair (BER), NEIL1 or NEIL2, POLB, LIG3:XRCC1 and PNKP dissociate from repaired DNA (Wiederhold et al. 2004, Das et al. 2006).
Literature References
PubMed ID Title Journal Year
16982218 NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in human cells

Karimi-Busheri, F, Wang, H, Weinfeld, M, Mitra, S, Hazra, TK, Kedar, P, Wilson, SH, Leppard, JB, Prasad, R, Boldogh, I, Tomkinson, AE, Wiederhold, L, Das, A

DNA Repair (Amst.) 2006
15260972 AP endonuclease-independent DNA base excision repair in human cells

Karimi-Busheri, F, Weinfeld, M, Mitra, S, Wiederhold, L, Izumi, T, Hazra, TK, Kedar, P, Wilson, SH, Leppard, JB, Prasad, R, Rasouli-Nia, A, Tomkinson, AE

Mol. Cell 2004
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Authored
Orlic-Milacic, M  (2014-12-04)
Reviewed
Borowiec, JA  (2014-12-22)
Created
Orlic-Milacic, M  (2014-11-21)
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