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NEIL1:DHU-dsDNA
Stable Identifier
R-HSA-5649652
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
DNA Repair (Homo sapiens)
Base Excision Repair (Homo sapiens)
Base-Excision Repair, AP Site Formation (Homo sapiens)
Depyrimidination (Homo sapiens)
Cleavage of the damaged pyrimidine (Homo sapiens)
NEIL1 cleaves DHU from damaged DNA (Homo sapiens)
NEIL1:DHU-dsDNA [nucleoplasm] (Homo sapiens)
Recognition and association of DNA glycosylase with site containing an affected pyrimidine (Homo sapiens)
NEIL1 recognizes and binds DHU-dsDNA (Homo sapiens)
NEIL1:DHU-dsDNA [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
11904416
Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA
Proc. Natl. Acad. Sci. U.S.A.
2002
Participants
components
DHU-dsDNA [nucleoplasm] (Homo sapiens)
NEIL1 [nucleoplasm] (Homo sapiens)
Participant Of
input
NEIL1 cleaves DHU from damaged DNA
output
NEIL1 recognizes and binds DHU-dsDNA
Inferred To
NEIL1:DHU-dsDNA [nucleoplasm] (Bos taurus)
NEIL1:DHU-dsDNA [nucleoplasm] (Canis familiaris)
NEIL1:DHU-dsDNA [nucleoplasm] (Danio rerio)
NEIL1:DHU-dsDNA [nucleoplasm] (Gallus gallus)
NEIL1:DHU-dsDNA [nucleoplasm] (Mus musculus)
NEIL1:DHU-dsDNA [nucleoplasm] (Rattus norvegicus)
NEIL1:DHU-dsDNA [nucleoplasm] (Sus scrofa)
NEIL1:DHU-dsDNA [nucleoplasm] (Taeniopygia guttata)
NEIL1:DHU-dsDNA [nucleoplasm] (Xenopus tropicalis)
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