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FapyA-dsDNA [nucleoplasm]
Stable Identifier
R-HSA-5643990
Type
Genes and Transcripts [GenomeEncodedEntity]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Double strand DNA containing 4,6-diamino-5-formamido-pyrimidine
Locations in the PathwayBrowser
Expand all
DNA Repair (Homo sapiens)
Base Excision Repair (Homo sapiens)
Base-Excision Repair, AP Site Formation (Homo sapiens)
Depyrimidination (Homo sapiens)
Cleavage of the damaged pyrimidine (Homo sapiens)
NEIL1 cleaves FapyA from damaged DNA (Homo sapiens)
NEIL1:FapyA-dsDNA [nucleoplasm] (Homo sapiens)
FapyA-dsDNA [nucleoplasm] (Homo sapiens)
Recognition and association of DNA glycosylase with site containing an affected pyrimidine (Homo sapiens)
NEIL1 recognizes and binds FapyA-dsDNA (Homo sapiens)
FapyA-dsDNA [nucleoplasm] (Homo sapiens)
NEIL1:FapyA-dsDNA [nucleoplasm] (Homo sapiens)
FapyA-dsDNA [nucleoplasm] (Homo sapiens)
NTHL1 glycosylase mediated recognition and binding of formamidopyrimidine (FapyA) (Homo sapiens)
FapyA-dsDNA [nucleoplasm] (Homo sapiens)
Disease (Homo sapiens)
Diseases of DNA repair (Homo sapiens)
Diseases of Base Excision Repair (Homo sapiens)
Defective Base Excision Repair Associated with NEIL1 (Homo sapiens)
NEIL1 G83D does not cleave FapyA (Homo sapiens)
NEIL1 G83D:FapyA-dsDNA [nucleoplasm] (Homo sapiens)
FapyA-dsDNA [nucleoplasm] (Homo sapiens)
Defective Base Excision Repair Associated with NTHL1 (Homo sapiens)
Defective NTHL1 substrate binding (Homo sapiens)
Defective NTHL1 truncation mutants do not bind formamidopyrimidine (FapyA) (Homo sapiens)
FapyA-dsDNA [nucleoplasm] (Homo sapiens)
Participates
as an input of
Defective NTHL1 truncation mutants do not bind formamidopyrimidine (FapyA) (Homo sapiens)
NEIL1 recognizes and binds FapyA-dsDNA (Homo sapiens)
NTHL1 glycosylase mediated recognition and binding of formamidopyrimidine (FapyA) (Homo sapiens)
as a component of
NEIL1 G83D:FapyA-dsDNA [nucleoplasm] (Homo sapiens)
NEIL1:FapyA-dsDNA [nucleoplasm] (Homo sapiens)
Inferred To
Ghost homologue of FapyA-dsDNA [nucleoplasm]
(Bos taurus)
Ghost homologue of FapyA-dsDNA [nucleoplasm]
(Canis familiaris)
Ghost homologue of FapyA-dsDNA [nucleoplasm]
(Danio rerio)
Ghost homologue of FapyA-dsDNA [nucleoplasm]
(Gallus gallus)
Ghost homologue of FapyA-dsDNA [nucleoplasm]
(Mus musculus)
Ghost homologue of FapyA-dsDNA [nucleoplasm]
(Rattus norvegicus)
Ghost homologue of FapyA-dsDNA [nucleoplasm]
(Sus scrofa)
Ghost homologue of FapyA-dsDNA [nucleoplasm]
(Xenopus tropicalis)
Cross References
ChEBI
16991
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