Reactome | RP2:ARL3:GDP:UNC119B dissociates

RP2:ARL3:GDP:UNC119B dissociates

Stable Identifier

R-HSA-5638016

Type

Reaction [dissociation]

Species

Homo sapiens

Compartment

cilium

ReviewStatus

5/5

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ARL3 hydrolysis of GTP promotes the release of UNC119B, dissociating the complex (Wright et al, 2011; reveiwed in Schwarz et al, 2012).

Literature References

PubMed ID	Title	Journal	Year
22085962	An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium Sengupta, P, Kwong, M, Baye, LM, Sang, L, Sheffield, VC, Wright, KJ, Slusarski, DC, Jackson, PK, Pretorius, PR, Wang, W, Mukhopadhyay, S, Olivier-Mason, A	Genes Dev.	2011
22884633	Arl3 and RP2 mediated assembly and traffic of membrane associated cilia proteins Cheetham, ME, Schwarz, N, Hardcastle, AJ	Vision Res.	2012