Reactome | RP2:ARL3:GDP:UNC119B dissociates

RP2:ARL3:GDP:UNC119B dissociates

Stable Identifier

R-HSA-5638016

Type

Reaction [dissociation]

Species

Homo sapiens

Compartment

cilium

ReviewStatus

5/5

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ARL3 hydrolysis of GTP promotes the release of UNC119B, dissociating the complex (Wright et al, 2011; reviewed in Schwarz et al, 2012).

Literature References

PubMed ID	Title	Journal	Year
22085962	An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium Wright, KJ, Baye, LM, Olivier-Mason, A, Mukhopadhyay, S, Sang, L, Kwong, M, Wang, W, Pretorius, PR, Sheffield, VC, Sengupta, P, Slusarski, DC, Jackson, PK	Genes Dev.	2011
22884633	Arl3 and RP2 mediated assembly and traffic of membrane associated cilia proteins Schwarz, N, Hardcastle, AJ, Cheetham, ME	Vision Res.	2012