Binding of PI3K to complex of GRB2:GAB1 and p-EGFRvIII

Stable Identifier
R-HSA-5637765
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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EGFRvIII cancer mutant is assumed to recruit the PI3K complex PIK3CA:PIK3R1 in a manner similar to wild-type EGFR (Rodrigues et al. 2000).

Literature References
PubMed ID Title Journal Year
10648629 A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling

Rodrigues, GA, Falasca, M, Zhang, Z, Ong, SH, Schlessinger, J

Mol Cell Biol 2000
Participants
Participant Of
Normal reaction
Disease
Name Identifier Synonyms
cancer 162 malignant tumor, malignant neoplasm, primary cancer
Authored
Reviewed
Created
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