TNFSF10:TNFRSF10A,B:FADD:CASP10(1-521) [plasma membrane]

Stable Identifier
R-HSA-5637463
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
TRAIL:TRAIL receptor-1,2 Trimer:FADD:Caspase-10 precursor complex
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
12198154 Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8

Sprick, MR, Rieser, E, Stahl, H, Grosse-Wilde, A, Weigand, MA, Walczak, H

EMBO J 2002
11717445 Caspase-10 is an initiator caspase in death receptor signaling

Wang, J, Chun, HJ, Wong, W, Spencer, DM, Lenardo, MJ

Proc Natl Acad Sci U S A 2001
Participants
components
Participant Of
output
Inferred To
TNFSF10:TNFRSF10A,B:FADD:CASP10(1-521) [plasma membrane] (Danio rerio)
TNFSF10:TNFRSF10A,B:FADD:CASP10(1-521) [plasma membrane] (Gallus gallus)
TNFSF10:TNFRSF10A,B:FADD:CASP10(1-521) [plasma membrane] (Sus scrofa)
TNFSF10:TNFRSF10A,B:FADD:CASP10(1-521) [plasma membrane] (Xenopus tropicalis)