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GPR161 [endocytic vesicle membrane]
Stable Identifier
R-HSA-5635021
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endocytic vesicle membrane
Icon
Locations in the PathwayBrowser for interactor UniProt:Q8TBA6 GOLGA5
Expand all
Signal Transduction (Homo sapiens)
Signaling by Hedgehog (Homo sapiens)
Hedgehog 'on' state (Homo sapiens)
GPR161 is internalized (Homo sapiens)
GPR161 [endocytic vesicle membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8N6U8 GPR161
Gene Names
GPR161
Chain
chain:1-529
Reference Genes
BioGPS Gene:23432 GPR161
COSMIC (genes):GPR161 GPR161
CTD Gene:23432 GPR161
dbSNP Gene:23432 GPR161
ENSEMBL:ENSG00000143147 GPR161
ENSEMBL_homo_sapiens_GENE:ENSG00000143147.15 GPR161
HGNC:23694 GPR161
KEGG Gene (Homo sapiens):23432 GPR161
Monarch:23432 GPR161
NCBI Gene:23432 GPR161
OMIM:612250 GPR161
UCSC:Q8N6U8 GPR161
Reference Transcript
RefSeq:XM_005245056.2 GPR161
RefSeq:XM_011509378.1 GPR161
RefSeq:NM_001267612.1 GPR161
RefSeq:NM_001267610.1 GPR161
RefSeq:XM_005245055.2 GPR161
RefSeq:XM_011509377.1 GPR161
RefSeq:XM_011509376.2 GPR161
RefSeq:XM_017000862.1 GPR161
RefSeq:NM_153832.2 GPR161
RefSeq:XM_011509375.2 GPR161
RefSeq:XM_017000861.1 GPR161
RefSeq:XM_017000860.1 GPR161
RefSeq:NM_001267609.1 GPR161
RefSeq:NM_001267614.1 GPR161
RefSeq:NM_001267613.1 GPR161
RefSeq:XM_005245057.4 GPR161
RefSeq:XM_017000859.1 GPR161
Other Identifiers
11742775_a_at
11742776_s_at
11749295_a_at
16696073
206971_PM_at
206971_at
206972_PM_s_at
206972_s_at
214104_PM_at
214104_at
230369_PM_at
230369_at
232350_3p_x_at
232350_PM_x_at
232350_x_at
23432
235961_PM_at
235961_at
2442913
2442914
2442915
2442916
2442917
2442918
2442919
2442920
2442921
2442922
2442924
2442931
2442932
2442939
2442946
2442947
2442948
2442949
2442952
2442957
2442958
2442960
2442961
2442962
2442963
2442964
2442965
2442966
40300_g_at
40301_at
48259_at
55977_at
77927_i_at
77929_r_at
7922108
A_23_P103532
A_23_P303455
A_23_P354314
A_32_P497742
GE81746
GO:0004930
GO:0005515
GO:0005768
GO:0005886
GO:0005929
GO:0007165
GO:0007186
GO:0007189
GO:0016020
GO:0023052
GO:0030666
GO:0031410
GO:0042995
GO:0043005
GO:0043226
GO:0048856
GO:0055037
GO:0060089
GO:0060170
GO:0097386
GO:1901621
HMNXSV003049054
Hs.21606.0.A1_3p_at
Hs.271809.0.S1_3p_x_at
Hs.301642.1.S1_3p_at
Hs.85893.0.A1_3p_at
ILMN_1658586
ILMN_1773940
PH_hs_0023354
PH_hs_0039137
TC01005921.hg
g6677700_3p_a_at
g6677700_3p_x_at
Participates
as an output of
GPR161 is internalized (Homo sapiens)
Other forms of this molecule
GPR161 [ciliary membrane]
Inferred To
GPR161 [endocytic vesicle membrane]
(Bos taurus)
GPR161 [endocytic vesicle membrane]
(Canis familiaris)
GPR161 [endocytic vesicle membrane]
(Gallus gallus)
GPR161 [endocytic vesicle membrane]
(Sus scrofa)
Gpr161 [endocytic vesicle membrane]
(Mus musculus)
Gpr161 [endocytic vesicle membrane]
(Rattus norvegicus)
gpr161 [endocytic vesicle membrane]
(Danio rerio)
gpr161 [endocytic vesicle membrane]
(Xenopus tropicalis)
Cross References
RefSeq
XP_016856348.1
,
XP_011507678.1
,
NP_001254542.1
,
NP_722561.1
,
XP_016856351.1
,
XP_011507677.1
,
XP_005245113.1
,
NP_001254543.1
,
XP_016856350.1
,
XP_005245114.1
,
XP_005245112.1
,
XP_016856349.1
,
NP_001254539.1
,
NP_001254541.1
,
XP_011507679.1
,
XP_011507680.1
,
NP_001254538.1
Guide to Pharmacology - Targets
141
OpenTargets
ENSG00000143147
HPA
ENSG00000143147-GPR161
GeneCards
Q8N6U8
Ensembl
ENST00000537209
,
ENSP00000356809
,
ENST00000546300
,
ENSP00000506967
,
ENST00000367838
,
ENSP00000437576
,
ENSG00000143147
,
ENST00000367836
,
ENST00000367835
,
ENSP00000441039
,
ENSP00000444348
,
ENSP00000356810
,
ENSP00000356812
,
ENST00000539777
,
ENST00000682931
PRO
Q8N6U8
Pharos - Targets
Q8N6U8
Orphanet
23218
PDB
8SMV
,
8KH4
Interactors (12)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P17612 PRKACA
4
PRKACA [mitochondrial matrix]
(R-HSA-9838291)
PRKACA [ciliary base]
(R-HSA-5610402)
PRKACA [nucleoplasm]
(R-HSA-111936)
PRKACA [cytosol]
(R-HSA-57844)
0.643
4
UniProt:P52803 EFNA5
3
EFNA5 (21-?) N-ter [extracellular region]
(R-HSA-3928456)
EFNA5 (?-203) C-ter [plasma membrane]
(R-HSA-3928431)
EFNA5 [plasma membrane]
(R-HSA-2682331)
0.556
3
UniProt:O75841 UPK1B
0.556
3
UniProt:Q8N6F1-2 CLDN19
0.556
3
UniProt:P21964 COMT
2
COMT [plasma membrane]
(R-HSA-379386)
COMT [cytosol]
(R-HSA-175974)
0.556
3
UniProt:Q9BRI3 SLC30A2
2
SLC30A2 [endosome membrane]
(R-HSA-435363)
SLC30A2 [synaptic vesicle membrane]
(R-HSA-4084714)
0.556
3
UniProt:Q8TBA6 GOLGA5
2
GOLGA5 [transport vesicle]
(R-HSA-8847517)
GOLGA5 [Golgi membrane]
(R-HSA-8847514)
0.527
2
UniProt:P31321 PRKAR1B
2
PRKAR1B [cytosol]
(R-HSA-57838)
PRKAR1B [ciliary base]
(R-HSA-5610409)
0.527
4
UniProt:P22694 PRKACB
3
PRKACB [ciliary base]
(R-HSA-5610404)
PRKACB [cytosol]
(R-HSA-57846)
PRKACB [nucleoplasm]
(R-HSA-111937)
0.527
3
UniProt:O75317 USP12
1
USP12 [nucleoplasm]
(R-HSA-5696907)
0.527
2
UniProt:P22612 PRKACG
3
PRKACG [ciliary base]
(R-HSA-5610405)
PRKACG [cytosol]
(R-HSA-57848)
PRKACG [nucleoplasm]
(R-HSA-111938)
0.527
3
UniProt:P10644 PRKAR1A
4
PRKAR1A(1-183)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9713476)
PRKAR1A(1-183)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9713471)
PRKAR1A [ciliary base]
(R-HSA-5610408)
PRKAR1A [cytosol]
(R-HSA-57836)
0.527
3
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