TP53 binds the PTEN promoter

Stable Identifier
R-HSA-5632939
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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PTEN (phosphatase and tensin homolog deleted in chromosome 10) is a tumor suppressor gene that is deleted or mutated in a variety of human cancers. TP53 (p53) binds to the p53-binding site at the PTEN promoter level (Stambolic et al. 2001).

Literature References
PubMed ID Title Journal Year
11545734 Regulation of PTEN transcription by p53

Stambolic, V, MacPherson, D, Sas, D, Lin, Y, Snow, B, Jang, Y, Benchimol, S, Mak, TW

Mol. Cell 2001
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