HENMT1 methylates 2' hydroxyl at 3' end of piRNA in 6xMeR-PIWIL2:piRNA:TDRD1:TDRD12:DDX4:ASZ:MOV10L1

Stable Identifier
R-HSA-5629218
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
HENMT1 methylates 2' hydroxyl at 3' end of piRNA in 6xMeR-PIWIL2:piRNA:TDRD1:TDRD12:DDX4:ASZ:MOV10L1
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

As inferred from mouse homologs, HENMT1 transfers a methyl group from S-adenosylmethionine to the 2' hydroxyl group at the 3' end of piRNA bound to the PIWIL2 complex in the cytosol.

Participants
Input
Output
Participates
as an event of
Catalyst Activity

O-methyltransferase activity of HENMT1 [cytosol]

Physical Entity
HENMT1 [cytosol] (Homo sapiens)
Activity
O-methyltransferase activity (GO:0008171)
Inferred From
Henmt1 methylates 2' hydroxyl at 3' end of piRNA in Asz1:Ddx4:Mov10l1:6xMeR-Piwil2:piRNA:Tdrd1:Tdrd12 (Mus musculus)
Authored
May, B  (2014-10-25)
Reviewed
Saito, K  (2014-10-25)
Created
May, B  (2014-10-25)
Cite Us!