HENMT1 methylates 2' hydroxyl at 3' end of piRNA in 6xMeR-PIWIL2:piRNA:TDRD1:TDRD12:DDX4:ASZ:MOV10L1

Stable Identifier
R-HSA-5629218
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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HENMT1 methylates 2' hydroxyl at 3' end of piRNA in 6xMeR-PIWIL2:piRNA:TDRD1:TDRD12:DDX4:ASZ:MOV10L1
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As inferred from mouse homologs, HENMT1 transfers a methyl group from S-adenosylmethionine to the 2' hydroxyl group at the 3' end of piRNA bound to the PIWIL2 complex in the cytosol.
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Output
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as an event of
Catalyst Activity

O-methyltransferase activity of HENMT1 [cytosol]

Physical Entity
HENMT1 [cytosol] (Homo sapiens)
Activity
O-methyltransferase activity (GO:0008171)
Inferred From
Henmt1 methylates 2' hydroxyl at 3' end of piRNA in Asz1:Ddx4:Mov10l1:6xMeR-Piwil2:piRNA:Tdrd1:Tdrd12 (Mus musculus)
Authored
May, B  (2014-10-25)
Reviewed
Saito, K  (2014-10-25)
Created
May, B  (2014-10-25)
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