TP53 binds the TIGAR gene

Stable Identifier
R-HSA-5628899
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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TP53 binds the TIGAR gene
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TIGAR gene possesses two TP53 (p53) binding sites, one upstream of the first exon and another within the first intron. TP53 can bind both sites, with a higher affinity for the intronic site (Bensaad et al. 2006).

Literature References
PubMed ID Title Journal Year
16839880 TIGAR, a p53-inducible regulator of glycolysis and apoptosis

Vidal, MN, Bensaad, K, Selak, MA, Tsuruta, A, Nakano, K, Gottlieb, E, Bartrons, R, Vousden, KH

Cell 2006
Participants
Input
Output
Participates
as an event of
Authored
Orlic-Milacic, M  (2014-12-23)
Reviewed
Zaccara, S  (2016-02-04)
Inga, A  (2016-02-04)
Wang, PY  (2014-12-30)
Hwang, PM  (2014-12-30)
Kang, JG  (2014-12-30)
Created
Orlic-Milacic, M  (2014-10-24)
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