TP53 binds the TIGAR gene

Stable Identifier
R-HSA-5628899
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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TP53 binds the TIGAR gene
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TIGAR gene possesses two TP53 (p53) binding sites, one upstream of the first exon and another within the first intron. TP53 can bind both sites, with a higher affinity for the intronic site (Bensaad et al. 2006).
Literature References
PubMed ID Title Journal Year
16839880 TIGAR, a p53-inducible regulator of glycolysis and apoptosis

Vidal, MN, Bensaad, K, Selak, MA, Tsuruta, A, Nakano, K, Gottlieb, E, Bartrons, R, Vousden, KH

Cell 2006
Participants
Input
Output
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as an event of
Authored
Orlic-Milacic, M  (2014-12-23)
Reviewed
Zaccara, S  (2016-02-04)
Inga, A  (2016-02-04)
Wang, PY  (2014-12-30)
Hwang, PM  (2014-12-30)
Kang, JG  (2014-12-30)
Created
Orlic-Milacic, M  (2014-10-24)
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