Reactome | SOX7 [nucleoplasm]

SOX7 [nucleoplasm]

Stable Identifier

R-HSA-5627712

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Transcription factor SOX-7, SOX7_HUMAN

Locations in the PathwayBrowser

Expand all

Signal Transduction (Homo sapiens)

- Signaling by WNT (Homo sapiens)
  - TCF dependent signaling in response to WNT (Homo sapiens)
    - Deactivation of the beta-catenin transactivating complex (Homo sapiens)
      - Beta-catenin binds SOX proteins (Homo sapiens)
        
        CTNNB1:SRY,SOX2,SOX3,SOX4,SOX6,SOX7,SOX9,SOX17 [nucleoplasm] (Homo sapiens)
        
        SRY,SOX2,SOX3,SOX4,SOX6,SOX7,SOX9,SOX17 [nucleoplasm] (Homo sapiens)
        
        SOX7 [nucleoplasm] (Homo sapiens)
        
        SRY,SOX2,SOX3,SOX4,SOX6,SOX7,SOX9,SOX17 [nucleoplasm] (Homo sapiens)
        
        SOX7 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9BT81 SOX7

Gene Names

SOX7

Chain

chain:1-388

Reference Genes

BioGPS Gene:83595 SOX7

COSMIC (genes):SOX7 SOX7

CTD Gene:83595 SOX7

dbSNP Gene:83595 SOX7

ENSEMBL:ENSG00000171056 SOX7

ENSEMBL_homo_sapiens_GENE:ENSG00000171056.8 SOX7

ENSEMBL_homo_sapiens_GENE:ENSG00000285438.2 SOX7

HGNC:18196 SOX7

KEGG Gene (Homo sapiens):83595 SOX7

Monarch:83595 SOX7

NCBI Gene:83595 SOX7

OMIM:612202 SOX7

UCSC:Q9BT81 SOX7

Reference Transcript

RefSeq:NM_031439.3 SOX7

Other Identifiers

11727503_at

11727504_at

11751016_s_at

17074567

224013_3p_s_at

224013_PM_s_at

224013_s_at

228698_PM_at

228698_at

3124155

3124156

3124160

3124161

3124164

3124165

3124166

3124167

51610_at

71277_r_at

8149289

83595

A_23_P169738

A_23_P306987

A_24_P226782

GE83244

GO:0000785

GO:0000976

GO:0000978

GO:0000981

GO:0001706

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0006351

GO:0006355

GO:0006357

GO:0008285

GO:0009653

GO:0023052

GO:0030154

GO:0043226

GO:0043280

GO:0043565

GO:0045892

GO:0045893

GO:0048856

GO:0060828

GO:0140110

GO:1990837

HMNXSV003016521

Hs.17404.0.A1_3p_at

ILMN_1815032

ILMN_2134056

PH_hs_0012328

TC08002610.hg

g13279163_3p_a_at

g13279163_3p_at

g13279163_3p_x_at

Participates

as a member of

SRY,SOX2,SOX3,SOX4,SOX6,SOX7,SOX9,SOX17 [nucleoplasm] (Homo sapiens)

Inferred To

sox-4 [nucleoplasm] (Caenorhabditis elegans)

Sox14 [nucleoplasm] (Drosophila melanogaster)

Sox7 [nucleoplasm] (Mus musculus)

Sox7 [nucleoplasm] (Rattus norvegicus)

SoxN [nucleoplasm] (Drosophila melanogaster)

sox7 [nucleoplasm] (Xenopus tropicalis)

D [nucleoplasm] (Drosophila melanogaster)

sox-2 [nucleoplasm] (Caenorhabditis elegans)

sox-3 [nucleoplasm] (Caenorhabditis elegans)

Homologues of SOX7 [nucleoplasm] (Caenorhabditis elegans)

Homologues of SOX7 [nucleoplasm] (Drosophila melanogaster)

Sox21b [nucleoplasm] (Drosophila melanogaster)

sem-2 [nucleoplasm] (Caenorhabditis elegans)

Sox21a [nucleoplasm] (Drosophila melanogaster)

SOX7 [nucleoplasm] (Bos taurus)

SOX7 [nucleoplasm] (Canis familiaris)

SOX7 [nucleoplasm] (Danio rerio)

SOX7 [nucleoplasm] (Gallus gallus)

SOX7 [nucleoplasm] (Sus scrofa)

Sox15 [nucleoplasm] (Drosophila melanogaster)

Cross References

RefSeq

NP_113627.1

OpenTargets

ENSG00000171056

GeneCards

Q9BT81

HPA

ENSG00000171056-SOX7

Ensembl

ENSG00000285438, ENSP00000301921, ENST00000304501, ENSP00000495029, ENST00000646538, ENSG00000171056

PRO

Q9BT81

Pharos - Targets

Q9BT81

Orphanet

24939

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8N9R8 SCAI	1	SCAI [nucleoplasm] (R-HSA-5666012)	0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	15
UniProt:O76003 GLRX3	1	GLRX3 [cytosol] (R-HSA-5691202)	0.556	3