RHOQ binds GOPC:CFTR

Stable Identifier
R-HSA-5627072
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Golgi-associated vesicle membrane
ReviewStatus
5/5
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RHOQ binds GOPC:CFTR
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GTP-bound RHO GTPase RHOQ (TC10) binds GOPC (also known as PIST, CAL or FIG) dimer (Neudauer et al. 2001, Cheng et al. 2005) in complex with CFTR (cystic fibrosis transmembrane conductance regulator) on Golgi-associated vesicles (Cheng et al. 2005).

Literature References
PubMed ID Title Journal Year
15546864 Regulation of cystic fibrosis transmembrane regulator trafficking and protein expression by a Rho family small GTPase TC10

Cheng, J, Guggino, WB, Wang, H

J. Biol. Chem. 2005
11162552 PIST: a novel PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10

Joberty, G, Macara, IG, Neudauer, CL

Biochem. Biophys. Res. Commun. 2001
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Orthologous Events
RHOQ binds GOPC:CFTR (Bos taurus)
RHOQ binds GOPC:CFTR (Caenorhabditis elegans)
RHOQ binds GOPC:CFTR (Danio rerio)
RHOQ binds GOPC:CFTR (Gallus gallus)
RHOQ binds GOPC:CFTR (Mus musculus)
RHOQ binds GOPC:CFTR (Sus scrofa)
RHOQ binds GOPC:CFTR (Xenopus tropicalis)
Authored
Orlic-Milacic, M  (2014-10-24)
Rivero Crespo, F  (2014-12-26)
Reviewed
Das, ME  (2021-05-17)
Fort, P  (2021-02-05)
Created
Orlic-Milacic, M  (2014-10-14)
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