Reactome | SOX17 [nucleoplasm]

SOX17 [nucleoplasm]

Stable Identifier

R-HSA-5625834

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Transcription factor SOX-17, SOX17_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9H6I2 SOX17

Gene Names

SOX17

Chain

chain:1-414

Reference Genes

BioGPS Gene:64321 SOX17

COSMIC (genes):SOX17 SOX17

CTD Gene:64321 SOX17

dbSNP Gene:64321 SOX17

ENSEMBL:ENSG00000164736.6 SOX17

HGNC:18122 SOX17

KEGG Gene (Homo sapiens):64321 SOX17

Monarch:64321 SOX17

NCBI Gene:64321 SOX17

OMIM:610928 SOX17

UCSC:Q9H6I2 SOX17

Reference Transcript

RefSeq:NM_022454.3 SOX17

Other Identifiers

11743872_a_at

11743873_x_at

11743874_a_at

17068972

219993_PM_at

219993_at

230943_PM_at

230943_at

3098550

3098551

3098552

3098554

3098555

3098556

3098557

3098558

3098559

3098560

55547_at

61415_at

63045_at

64321

8146462

A_14_P202396

A_23_P82775

A_24_P46946

GE63173

GO:0000785

GO:0000976

GO:0000978

GO:0000981

GO:0001228

GO:0001525

GO:0001570

GO:0001656

GO:0001706

GO:0001714

GO:0001828

GO:0001947

GO:0003142

GO:0003143

GO:0003151

GO:0003308

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005667

GO:0005694

GO:0006351

GO:0006355

GO:0006357

GO:0007283

GO:0007369

GO:0007492

GO:0007493

GO:0007507

GO:0008013

GO:0009653

GO:0010467

GO:0010628

GO:0016055

GO:0021903

GO:0022414

GO:0023019

GO:0023052

GO:0030154

GO:0030163

GO:0030178

GO:0030308

GO:0031648

GO:0035050

GO:0035987

GO:0042074

GO:0043226

GO:0043565

GO:0045595

GO:0045732

GO:0045893

GO:0045944

GO:0045995

GO:0048568

GO:0048617

GO:0048856

GO:0048863

GO:0048866

GO:0048870

GO:0050821

GO:0060214

GO:0060913

GO:0060914

GO:0060956

GO:0061009

GO:0061010

GO:0061031

GO:0061629

GO:0072091

GO:0072189

GO:0090090

GO:0140110

GO:1903226

GO:1990830

GO:2000035

GO:2000043

GO:2000738

HMNXSV003033224

Hs.98367.0.A1_3p_at

ILMN_1671092

PH_hs_0022233

TC08000376.hg

g11967990_3p_at

Participates

as an output of

Expression of SOX17 in definitive endoderm (Homo sapiens)

as a member of

This entity regulates

Positively

Expression of E-cadherin (CDH1) in definitive endoderm (Homo sapiens)

Inferred To

Sox17 [nucleoplasm] (Mus musculus)

Sox17 [nucleoplasm] (Rattus norvegicus)

sox17a [nucleoplasm] (Xenopus tropicalis)

SOX17 [nucleoplasm] (Bos taurus)

SOX17 [nucleoplasm] (Canis familiaris)

SOX17 [nucleoplasm] (Danio rerio)

SOX17 [nucleoplasm] (Gallus gallus)

SOX17 [nucleoplasm] (Sus scrofa)

Sox15 [nucleoplasm] (Drosophila melanogaster)

Cross References

RefSeq

NP_071899.1

OpenTargets

ENSG00000164736

GeneCards

Q9H6I2

HPA

ENSG00000164736-SOX17

Ensembl

ENSP00000297316, ENSG00000164736, ENST00000297316

PRO

Q9H6I2

Pharos - Targets

Q9H6I2

Orphanet

20717

PDB

4A3N, 2YUL

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P35222 CTNNB1	20	CTNNB1 S45A [cytosol] (R-HSA-9663982) CTNNB1 S45F [cytosol] (R-HSA-4791268) CTNNB1 S45C [cytosol] (R-HSA-9663983) CTNNB1 S45Y [cytosol] (R-HSA-9663975) CTNNB1 S45N [cytosol] (R-HSA-9663984) CTNNB1 S45P [cytosol] (R-HSA-4791272) pT41,S45-CTNNB1 S37P [cytosol] (R-HSA-9663981) pT41,S45-CTNNB1 S37F [cytosol] (R-HSA-4839621) pT41,S45-CTNNB1 S37A [cytosol] (R-HSA-4839619) pT41,S45-CTNNB1 S37Y [cytosol] (R-HSA-9663978) pT41,S45-CTNNB1 S37C [cytosol] (R-HSA-4839617) pS37,T41,S45-CTNNB1 S33A [cytosol] (R-HSA-9663976) pS37,T41,S45-CTNNB1 S33T [cytosol] (R-HSA-9663977) pS37,T41,S45-CTNNB1 S33C [cytosol] (R-HSA-4839630) pS37,T41,S45-CTNNB1 S33F [cytosol] (R-HSA-4839628) pS37,T41,S45-CTNNB1 S33P [cytosol] (R-HSA-4839626) pS37,T41,S45-CTNNB1 S33Y [cytosol] (R-HSA-4839625) pS45-CTNNB1 T41N [cytosol] (R-HSA-9663980) pS45-CTNNB1 T41A [cytosol] (R-HSA-4836868) pS45-CTNNB1 T41I [cytosol] (R-HSA-4839612)	0.499	2
UniProt:Q12857 NFIA	1	NFIA [nucleoplasm] (R-HSA-60134)	0.471	2
UniProt:O00712 NFIB	1	NFIB [nucleoplasm] (R-HSA-60136)	0.471	2