Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
KLK2 Gene [nucleoplasm]
Stable Identifier
R-HSA-5625763
Type
DNA Sequence [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase Effectors (Homo sapiens)
RHO GTPases activate PKNs (Homo sapiens)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Homo sapiens)
Demethylase KDM1A binds KLK2 and KLK3 promoters (Homo sapiens)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Homo sapiens)
KLK2,3 genes [nucleoplasm] (Homo sapiens)
KLK2 Gene [nucleoplasm] (Homo sapiens)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] (Homo sapiens)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Homo sapiens)
KLK2,3 genes [nucleoplasm] (Homo sapiens)
KLK2 Gene [nucleoplasm] (Homo sapiens)
Demethylase KDM4C binds KLK2 and KLK3 promoters (Homo sapiens)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3:KDM4C [nucleoplasm] (Homo sapiens)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Homo sapiens)
KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Homo sapiens)
KLK2,3 genes [nucleoplasm] (Homo sapiens)
KLK2 Gene [nucleoplasm] (Homo sapiens)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Homo sapiens)
KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Homo sapiens)
KLK2,3 genes [nucleoplasm] (Homo sapiens)
KLK2 Gene [nucleoplasm] (Homo sapiens)
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Homo sapiens)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] (Homo sapiens)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Homo sapiens)
KLK2,3 genes [nucleoplasm] (Homo sapiens)
KLK2 Gene [nucleoplasm] (Homo sapiens)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Homo sapiens)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Homo sapiens)
KLK2,3 genes [nucleoplasm] (Homo sapiens)
KLK2 Gene [nucleoplasm] (Homo sapiens)
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Homo sapiens)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-H3 [nucleoplasm] (Homo sapiens)
KLK2,3 genes [nucleoplasm] (Homo sapiens)
KLK2 Gene [nucleoplasm] (Homo sapiens)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Homo sapiens)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Homo sapiens)
KLK2,3 genes [nucleoplasm] (Homo sapiens)
KLK2 Gene [nucleoplasm] (Homo sapiens)
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters (Homo sapiens)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3:KDM4C [nucleoplasm] (Homo sapiens)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Homo sapiens)
KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Homo sapiens)
KLK2,3 genes [nucleoplasm] (Homo sapiens)
KLK2 Gene [nucleoplasm] (Homo sapiens)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Homo sapiens)
KLK2,3 genes [nucleoplasm] (Homo sapiens)
KLK2 Gene [nucleoplasm] (Homo sapiens)
PKN1 in complex with AR positively regulates expression of KLK2 and KLK3 (Homo sapiens)
KLK2,3 genes [nucleoplasm] (Homo sapiens)
KLK2 Gene [nucleoplasm] (Homo sapiens)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-H3 [nucleoplasm] (Homo sapiens)
KLK2,3 genes [nucleoplasm] (Homo sapiens)
KLK2 Gene [nucleoplasm] (Homo sapiens)
PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters (Homo sapiens)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Homo sapiens)
KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Homo sapiens)
KLK2,3 genes [nucleoplasm] (Homo sapiens)
KLK2 Gene [nucleoplasm] (Homo sapiens)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Homo sapiens)
KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Homo sapiens)
KLK2,3 genes [nucleoplasm] (Homo sapiens)
KLK2 Gene [nucleoplasm] (Homo sapiens)
PKN1:AR complex binds promoters of KLK2 and KLK3 genes (Homo sapiens)
KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Homo sapiens)
KLK2,3 genes [nucleoplasm] (Homo sapiens)
KLK2 Gene [nucleoplasm] (Homo sapiens)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Homo sapiens)
KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Homo sapiens)
KLK2,3 genes [nucleoplasm] (Homo sapiens)
KLK2 Gene [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
ENSEMBL:ENSG00000167751 KLK2
Gene Names
KLK2
Participates
as a member of
KLK2,3 genes [nucleoplasm] (Homo sapiens)
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text