Reactome | KIF3B [ciliary tip]

KIF3B [ciliary tip]

Stable Identifier

R-HSA-5625378

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

ciliary tip

Synonyms

Kinesin-like protein KIF3B, KIF3B_HUMAN

Locations in the PathwayBrowser

Expand all

Organelle biogenesis and maintenance (Homo sapiens)

- Cilium Assembly (Homo sapiens)
  - Intraflagellar transport (Homo sapiens)
    - Anterograde IFT (Homo sapiens)
      - anterograde IFT trains [ciliary tip] (Homo sapiens)
        
        active kinesin-2 motors [ciliary tip] (Homo sapiens)
        
        Kinesin-2 motors [ciliary tip] (Homo sapiens)
        
        Kinesin-2 [ciliary tip] (Homo sapiens)
        
        KIF3A partners [ciliary tip] (Homo sapiens)
        
        KIF3B [ciliary tip] (Homo sapiens)
    - Assembly of the retrograde IFT train (Homo sapiens)
      - Kinesin-2 motors [ciliary tip] (Homo sapiens)
        
        Kinesin-2 [ciliary tip] (Homo sapiens)
        
        KIF3A partners [ciliary tip] (Homo sapiens)
        
        KIF3B [ciliary tip] (Homo sapiens)
      - retrograde IFT trains [ciliary tip] (Homo sapiens)
        
        Kinesin-2 motors [ciliary tip] (Homo sapiens)
        
        Kinesin-2 [ciliary tip] (Homo sapiens)
        
        KIF3A partners [ciliary tip] (Homo sapiens)
        
        KIF3B [ciliary tip] (Homo sapiens)
    - Retrograde IFT (Homo sapiens)
      - retrograde IFT trains [ciliary tip] (Homo sapiens)
        
        Kinesin-2 motors [ciliary tip] (Homo sapiens)
        
        Kinesin-2 [ciliary tip] (Homo sapiens)
        
        KIF3A partners [ciliary tip] (Homo sapiens)
        
        KIF3B [ciliary tip] (Homo sapiens)
    - The anterograde IFT train dissociates (Homo sapiens)
      - Kinesin-2 motors [ciliary tip] (Homo sapiens)
        
        Kinesin-2 [ciliary tip] (Homo sapiens)
        
        KIF3A partners [ciliary tip] (Homo sapiens)
        
        KIF3B [ciliary tip] (Homo sapiens)
      - anterograde IFT trains [ciliary tip] (Homo sapiens)
        
        active kinesin-2 motors [ciliary tip] (Homo sapiens)
        
        Kinesin-2 motors [ciliary tip] (Homo sapiens)
        
        Kinesin-2 [ciliary tip] (Homo sapiens)
        
        KIF3A partners [ciliary tip] (Homo sapiens)
        
        KIF3B [ciliary tip] (Homo sapiens)

External Reference Information

External Reference

UniProt:O15066 KIF3B

Gene Names

KIF3B, KIAA0359

Chain

initiator methionine:1, chain:1-747, chain:2-747

Reference Genes

BioGPS Gene:9371 KIF3B

COSMIC (genes):KIF3B KIF3B

CTD Gene:9371 KIF3B

dbSNP Gene:9371 KIF3B

ENSEMBL:ENSG00000101350 KIF3B

HGNC:6320 KIF3B

KEGG Gene (Homo sapiens):9371 KIF3B

Monarch:9371 KIF3B

NCBI Gene:9371 KIF3B

OMIM:603754 KIF3B

UCSC:O15066 KIF3B

Reference Transcript

RefSeq:NM_004798.3 KIF3B

Other Identifiers

0006770372

11716626_at

11716627_a_at

11716628_at

11752926_a_at

16912535

203943_at

225205_at

34713_at

3881825

3881826

3881827

3881828

3881829

3881830

3881831

3881834

3881836

3881837

3881838

3881840

3881841

3881842

3881843

3881844

3881853

44728_at

8061715

9371

A_14_P101904

A_23_P17560

A_24_P134372

A_24_P941824

GE53080

GE79933

GO:0000166

GO:0000278

GO:0002376

GO:0003674

GO:0003777

GO:0005515

GO:0005524

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005813

GO:0005815

GO:0005819

GO:0005829

GO:0005856

GO:0005871

GO:0005873

GO:0005874

GO:0005876

GO:0005929

GO:0006810

GO:0006890

GO:0007010

GO:0007018

GO:0007049

GO:0007052

GO:0007100

GO:0007368

GO:0008017

GO:0008089

GO:0008092

GO:0008150

GO:0008574

GO:0015031

GO:0015630

GO:0016020

GO:0016192

GO:0016887

GO:0016939

GO:0019886

GO:0019899

GO:0022607

GO:0030424

GO:0030496

GO:0030705

GO:0031267

GO:0032467

GO:0032991

GO:0035735

GO:0042995

GO:0043167

GO:0043226

GO:0048856

GO:0051301

GO:0070062

GO:0072383

GO:0090307

GO:0097542

GO:0120170

GO:0140014

GO:1904115

GO:1990939

HMNXSV003004221

Hs.301206.0.A1_3p_at

ILMN_1702279

ILMN_2081398

PH_hs_0015521

TC20000209.hg

TC20001187.hg

g4758645_3p_at

Participates

as a member of

KIF3A partners [ciliary tip] (Homo sapiens)

Other forms of this molecule

KIF3B [cilium]

KIF3B [cytosol]

Inferred To

kif3b [ciliary tip] (Danio rerio)

KIF3B [ciliary tip] (Gallus gallus)

KIF3B [ciliary tip] (Sus scrofa)

Klp68D [ciliary tip] (Drosophila melanogaster)

klp-11 [ciliary tip] (Caenorhabditis elegans)

Kif3b [ciliary tip] (Mus musculus)

Kif3b [ciliary tip] (Rattus norvegicus)

Cross References

RefSeq

NP_004789.1

OpenTargets

ENSG00000101350

GeneCards

O15066

HPA

ENSG00000101350-KIF3B

ZINC target

O15066

Ensembl

ENSG00000101350, ENST00000375712, ENSP00000364864

PRO

O15066

Pharos - Targets

O15066

Orphanet

24651

PDB

3B6U

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q92845 KIFAP3	3	KIFAP3 [ciliary tip] (R-HSA-5625382) KIFAP3 [cilium] (R-HSA-5624882) KIFAP3 [cytosol] (R-HSA-984736)	0.8	8
UniProt:Q9Y496 KIF3A	3	KIF3A [cytosol] (R-HSA-984767) KIF3A [ciliary tip] (R-HSA-5625377) KIF3A [cilium] (R-HSA-5610394)	0.725	4

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