Reactome | IFT27 [ciliary tip]

IFT27 [ciliary tip]

Stable Identifier

R-HSA-5625357

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

ciliary tip

Synonyms

IFT-B 27, IFT B, RABL4, RAYL

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9BW83 IFT27

Gene Names

IFT27, RABL4, RAYL

Chain

chain:1-186

Reference Genes

BioGPS Gene:11020 IFT27

COSMIC (genes):IFT27 IFT27

CTD Gene:11020 IFT27

dbSNP Gene:11020 IFT27

ENSEMBL:ENSG00000100360 IFT27

HGNC:18626 IFT27

Monarch:11020 IFT27

NCBI Gene:11020 IFT27

OMIM:615870 IFT27

UCSC:Q9BW83 IFT27

Reference Transcript

Other Identifiers

11020

11720865_a_at

16934621

205037_PM_at

205037_at

213784_PM_at

213784_at

243812_PM_at

243812_at

36075_at

36076_g_at

36077_at

3959830

3959831

3959832

3959833

3959834

3959835

3959836

3959837

3959839

3959840

3959841

3959842

3959844

3959845

3959846

3959847

3959849

3959851

3959852

3959853

3959854

3959855

69274_at

8075828

A_21_P0000600

A_23_P6447

A_33_P3399560

GE56069

GE858428

GE85960

GO:0000139

GO:0000166

GO:0001822

GO:0003824

GO:0003924

GO:0005515

GO:0005525

GO:0005634

GO:0005737

GO:0005794

GO:0005813

GO:0005815

GO:0005929

GO:0006886

GO:0007018

GO:0007224

GO:0007283

GO:0015031

GO:0016192

GO:0016787

GO:0022414

GO:0030154

GO:0030992

GO:0031514

GO:0035720

GO:0036126

GO:0042073

GO:0043226

GO:0044782

GO:0048856

GO:0060122

GO:0060271

GO:0090102

GO:0097225

GO:0097228

GO:0097542

HMNXSV003020794

HMNXSV003025332

Hs.196536.0.A1_3p_at

Hs.50267.1.S1_3p_x_at

ILMN_1746492

PH_hs_0019605

TC22000714.hg

TC22001331.hg

g9257237_3p_a_at

g9257237_3p_x_at

p25218

p33810

Participates

as a component of

IFT B* [ciliary tip] (Homo sapiens)

Other forms of this molecule

IFT27 [cilium]

Inferred To

Ift27 [ciliary tip] (Rattus norvegicus)

IFT27 [ciliary tip] (Bos taurus)

IFT27 [ciliary tip] (Canis familiaris)

IFT27 [ciliary tip] (Mus musculus)

IFT27 [ciliary tip] (Sus scrofa)

Ghost homologue of IFT27 [ciliary tip] (Caenorhabditis elegans)

Ghost homologue of IFT27 [ciliary tip] (Gallus gallus)

Cross References

ENSEMBL

ENST00000340630, ENST00000433985, ENSP00000343593, ENSP00000393541

OpenTargets

ENSG00000100360

HPA

ENSG00000100360-IFT27

PRO

Q9BW83

Pharos - Targets

Q9BW83

GlyGen

Q9BW83

Orphanet

IFT27

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y547 HSPB11	2	HSPB11 [ciliary tip] (R-HSA-5625342) HSPB11 [cilium] (R-HSA-5617628)	0.943	24
UniProt:Q13099 IFT88	8	PolyUb-Misfolded IFT88 [lysosomal lumen] (R-HSA-9660026) PolyUb-Misfolded IFT88 [cytosol] (R-HSA-9641125) Ub-Misfolded IFT88 [cytosol] (R-HSA-9641114) Misfolded IFT88 [cytosol] (R-HSA-9640115) Misfolded IFT88 [cilium] (R-HSA-9640106) IFT88 [cilium] (R-HSA-5610385) PolyUb-Misfolded IFT88 [late endosome lumen] (R-HSA-9660031) IFT88 [ciliary tip] (R-HSA-5625371)	0.724	9
UniProt:Q9UG01 IFT172	2	IFT172 [ciliary tip] (R-HSA-5625353) IFT172 [cilium] (R-HSA-5610383)	0.724	8
UniProt:Q9P2H3 IFT80	2	IFT80 [ciliary tip] (R-HSA-5625367) IFT80 [cilium] (R-HSA-5617613)	0.69	7
UniProt:Q9H7X7 IFT22	2	RABL5 [cilium] (R-HSA-5617605) RABL5 [ciliary tip] (R-HSA-5625388)	0.69	6
UniProt:Q8WYA0 IFT81	2	IFT81 [cilium] (R-HSA-5617769) IFT81 [ciliary tip] (R-HSA-5625369)	0.69	5
UniProt:A0AVF1 TTC26	2	TTC26 [ciliary tip] (R-HSA-5637962) TTC26 [cilium] (R-HSA-5637963)	0.69	6
UniProt:Q86WT1 IFT70A	2	TTC30A [ciliary tip] (R-HSA-5637966) TTC30A [cilium] (R-HSA-5637968)	0.69	6
UniProt:Q9Y366 IFT52	2	IFT52 [ciliary tip] (R-HSA-5625360) IFT52 [cilium] (R-HSA-5610387)	0.69	5
UniProt:Q9NQC8 IFT46	2	IFT46 [ciliary tip] (R-HSA-5625359) IFT46 [cilium] (R-HSA-5617617)	0.69	6
UniProt:Q8N4P2 IFT70B	2	TTC30B [ciliary tip] (R-HSA-5637970) TTC30B [cilium] (R-HSA-5637971)	0.69	5
UniProt:Q96LB3 IFT74	2	IFT74 [ciliary tip] (R-HSA-5625364) IFT74 [cilium] (R-HSA-5617616)	0.69	6
UniProt:Q86VQ0 LCA5			0.638	3
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.556	3
UniProt:Q8TDR0 TRAF3IP1	2	TRAF3IP1 [ciliary tip] (R-HSA-5625404) TRAF3IP1 [cilium] (R-HSA-5617603)	0.527	3
UniProt:Q96AJ1 CLUAP1	2	CLUAP [ciliary tip] (R-HSA-5637957) CLUAP [cilium] (R-HSA-5637960)	0.527	3
UniProt:Q9NWB7 IFT57	2	IFT57 [cilium] (R-HSA-5610389) IFT57 [ciliary tip] (R-HSA-5625363)	0.527	3
UniProt:Q8IY31 IFT20	3	IFT20 [ciliary tip] (R-HSA-5625355) IFT20 [Golgi membrane] (R-HSA-5617625) IFT20 [cilium] (R-HSA-5617624)	0.527	3
UniProt:Q6NTF9 RHBD2			0.508	2
UniProt:Q96SB8 SMC6	1	SMC6 [nucleoplasm] (R-HSA-2993777)	0.508	2

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