Reactome | DYNC2LI1 [cilium]

DYNC2LI1 [cilium]

Stable Identifier

R-HSA-5624862

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cilium

Synonyms

Cytoplasmic dynein 2 light intermediate chain 1, DC2L1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8TCX1 DYNC2LI1

Gene Names

DYNC2LI1, D2LIC, LIC3, CGI-60

Chain

chain:1-351

Reference Genes

BioGPS Gene:51626 DYNC2LI1

COSMIC (genes):DYNC2LI1 DYNC2LI1

CTD Gene:51626 DYNC2LI1

dbSNP Gene:51626 DYNC2LI1

ENSEMBL:ENSG00000138036 DYNC2LI1

HGNC:24595 DYNC2LI1

Monarch:51626 DYNC2LI1

NCBI Gene:51626 DYNC2LI1

OMIM:617083 DYNC2LI1

UCSC:Q8TCX1 DYNC2LI1

Reference Transcript

Other Identifiers

11732389_a_at

11735315_a_at

1554324_PM_s_at

1554324_s_at

16879540

203762_PM_s_at

203762_s_at

203763_PM_at

203763_at

241757_PM_x_at

241757_x_at

2479511

2479512

2479516

2479518

2479523

2479524

2479526

2479527

2479529

2479530

2479531

2479532

2479533

2479534

2479535

2479536

2479537

2479538

2479541

2479542

2479544

2479545

2479546

2479547

2479548

2479552

2479553

37197_s_at

37198_r_at

37199_at

51626

52347_at

61062_at

8041676

A_23_P502170

A_23_P502174

A_33_P3228340

GE58647

GO:0005515

GO:0005737

GO:0005794

GO:0005813

GO:0005815

GO:0005829

GO:0005856

GO:0005868

GO:0005874

GO:0005881

GO:0005929

GO:0005930

GO:0007018

GO:0007368

GO:0030030

GO:0030286

GO:0031514

GO:0035721

GO:0035735

GO:0035869

GO:0036064

GO:0043226

GO:0044782

GO:0045177

GO:0045504

GO:0060271

GO:0097542

GO:1902017

HMNXSV003004975

HMNXSV003005592

HMNXSV003022174

Hs.309257.0.A1_3p_at

Hs2.7627.2.S1_3p_s_at

ILMN_1712945

ILMN_1811836

ILMN_2281734

PH_hs_0023694

TC02000271.hg

g7706299_3p_at

Participates

as a component of

dynein-2 [cilium] (Homo sapiens)

Other forms of this molecule

DYNC2LI1 [ciliary tip]

Inferred To

DYNC2LI1 [cilium] (Bos taurus)

DYNC2LI1 [cilium] (Canis familiaris)

DYNC2LI1 [cilium] (Gallus gallus)

DYNC2LI1 [cilium] (Sus scrofa)

xbx-1 [cilium] (Caenorhabditis elegans)

Dync2li1 [cilium] (Mus musculus)

Dync2li1 [cilium] (Rattus norvegicus)

Cross References

ENSEMBL

ENST00000260605, ENSP00000385738, ENSP00000474032, ENST00000605786, ENST00000398823, ENSP00000381804, ENSP00000260605, ENST00000406852

OpenTargets

ENSG00000138036

HPA

ENSG00000138036-DYNC2LI1

PRO

Q8TCX1

Pharos - Targets

Q8TCX1

GlyGen

Q8TCX1

Orphanet

DYNC2LI1

PDB

6RLB, 8RGH, 6SC2

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P00441 SOD1	5	2xHC-SOD1 [cytosol] (R-HSA-3299726) SOD1 [cytosol] (R-HSA-350697) 2xHC-SOD1 [mitochondrial intermembrane space] (R-HSA-3777108) SOD1 [mitochondrial intermembrane space] (R-HSA-3777082) SOD1 [extracellular region] (R-HSA-350705)	0.499	3
UniProt:Q14203 DCTN1	7	DCTN1(1-1065)-ALK(1058-1620) fusion [cytosol] (R-HSA-9711969) DCTN1(1-599)-ALK(1058-1620) fusion [cytosol] (R-HSA-9711960) DCTN1(1-1177)-ALK(1058-1620) fusion [cytosol] (R-HSA-9701997) DCTN1(1-1065)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9711959) DCTN1(1-599)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9711953) DCTN1(1-1177)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9711962) DCTN1 [cytosol] (R-HSA-535580)	0.462	2