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LZTFL1 oligomer:BBSome [cytosol]
Stable Identifier
R-HSA-5624121
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Organelle biogenesis and maintenance (Homo sapiens)
Cilium Assembly (Homo sapiens)
Cargo trafficking to the periciliary membrane (Homo sapiens)
BBSome-mediated cargo-targeting to cilium (Homo sapiens)
ARL6:GTP and the BBSome target cargo to the primary cilium (Homo sapiens)
LZTFL1 oligomer:BBSome [cytosol] (Homo sapiens)
LZTFL1 binds the BBSome and prevents its traffic to the cilium (Homo sapiens)
LZTFL1 oligomer:BBSome [cytosol] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
22072986
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened
Seo, S
,
Searby, CC
,
Bugge, K
,
Zhang, Q
,
Sheffield, VC
,
Nachury, MV
,
Breslow, DK
PLoS Genet.
2011
Participants
components
BBSome [cytosol]
(Homo sapiens)
LZTFL1 oligomer [cytosol]
(Homo sapiens)
Participates
as an output of
LZTFL1 binds the BBSome and prevents its traffic to the cilium (Homo sapiens)
This entity regulates
Negatively
ARL6:GTP and the BBSome target cargo to the primary cilium
(Homo sapiens)
Inferred To
LZTFL1 oligomer:BBSome [cytosol]
(Bos taurus)
LZTFL1 oligomer:BBSome [cytosol]
(Caenorhabditis elegans)
LZTFL1 oligomer:BBSome [cytosol]
(Canis familiaris)
LZTFL1 oligomer:BBSome [cytosol]
(Gallus gallus)
LZTFL1 oligomer:BBSome [cytosol]
(Mus musculus)
LZTFL1 oligomer:BBSome [cytosol]
(Rattus norvegicus)
LZTFL1 oligomer:BBSome [cytosol]
(Sus scrofa)
LZTFL1 oligomer:BBSome [cytosol]
(Xenopus tropicalis)
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