Reactome | MyrG2-NPHP3 [cytosol]

MyrG2-NPHP3 [cytosol]

Stable Identifier

R-HSA-5624091

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q7Z494 NPHP3

Gene Names

NPHP3, KIAA2000

Chain

initiator methionine:, chain:2-1330

Reference Genes

BioGPS Gene:27031 NPHP3

COSMIC (genes):NPHP3 NPHP3

CTD Gene:27031 NPHP3

dbSNP Gene:27031 NPHP3

ENSEMBL:ENSG00000113971 NPHP3

HGNC:7907 NPHP3

Monarch:27031 NPHP3

NCBI Gene:27031 NPHP3

OMIM:608002 NPHP3

UCSC:Q7Z494 NPHP3

Reference Transcript

RefSeq:NM_153240.4 NPHP3

Other Identifiers

11732489_a_at

11732490_a_at

11763003_at

11763004_x_at

1553389_PM_at

1553389_at

235410_PM_at

235410_at

235432_PM_at

235432_at

2695704

2695705

2695706

2695707

2695708

2695709

2695710

2695711

2695713

2695714

2695715

2695716

2695717

2695718

2695719

2695720

2695721

2695722

2695723

2695724

2695726

2695728

2695729

2695730

2695731

2695732

2695734

2695735

2695736

2695737

2695741

2695742

2695747

2695748

2695749

2695750

2695751

2695752

2695753

2695754

2695755

2695756

2695757

2695758

2695759

2695760

2695761

2695762

27031

75630_at

8090737

90312_r_at

90313_at

90315_g_at

A_23_P328652

A_23_P393656

A_33_P3228072

A_33_P3228102

GO:0001822

GO:0001947

GO:0003283

GO:0005515

GO:0005576

GO:0005829

GO:0005929

GO:0006629

GO:0007018

GO:0007163

GO:0007368

GO:0016055

GO:0030198

GO:0030324

GO:0035469

GO:0043226

GO:0044782

GO:0045494

GO:0048496

GO:0048856

GO:0060026

GO:0060027

GO:0060271

GO:0060287

GO:0060993

GO:0071908

GO:0071909

GO:0071910

GO:0072189

GO:0090090

GO:0097543

GO:0097546

GO:1905515

GO:2000095

HMNXSV003028732

Hs.138479.0.A1_3p_at

Hs.154150.0.A1_3p_at

Hs2.350824.1.S1_3p_at

ILMN_1730539

PH_hs_0022039

TC03003093.hg

TC03003342.hg

Participates

as a member of

myristoylated ciliary cargo [cytosol] (Homo sapiens)

Other forms of this molecule

MyrG2-NPHP3 [cilium]

Inferred To

NPHP3 [cytosol] (Bos taurus)

NPHP3 [cytosol] (Canis familiaris)

Nphp3 [cytosol] (Mus musculus)

Nphp3 [cytosol] (Rattus norvegicus)

nphp3 [cytosol] (Danio rerio)

Modified Residues

Name

N-myristoylglycine at 2

Coordinate

PsiMod Name

N-myristoylglycine [MOD:00068]

PsiMod Definition

A protein modification that effectively converts a glycine residue to N-myristoylglycine.

Cross References

ENSEMBL

ENSP00000338766, ENSP00000508409, ENST00000337331, ENSP00000372769, ENST00000383282, ENST00000683570

OpenTargets

ENSG00000113971

HPA

ENSG00000113971-NPHP3

PRO

Q7Z494

Pharos - Targets

Q7Z494

Orphanet

NPHP3

PDB

5L7K

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:A6NIH7 UNC119B	2	UNC119B [cytosol] (R-HSA-5624097) UNC119B [cilium] (R-HSA-5618271)	0.59	3
UniProt:O15294 OGT	2	OGT [nucleoplasm] (R-HSA-3321845) OGT [cytosol] (R-HSA-9687814)	0.508	2