Reactome | CNG tetramer [Golgi membrane]

CNG tetramer [Golgi membrane]

Stable Identifier

R-HSA-5624059

Type

Complex

Species

Homo sapiens

Compartment

Golgi membrane

Locations in the PathwayBrowser

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Organelle biogenesis and maintenance (Homo sapiens)

- Cilium Assembly (Homo sapiens)
  - Cargo trafficking to the periciliary membrane (Homo sapiens)
    - VxPx cargo-targeting to cilium (Homo sapiens)
      - ARF4:GTP binds VxPx-motifs of membrane proteins (Homo sapiens)
        
        ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        CNG tetramer [Golgi membrane] (Homo sapiens)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        CNG tetramer [Golgi membrane] (Homo sapiens)
      - ASAP1 dimer binds membrane proteins (Homo sapiens)
        
        ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        CNG tetramer [Golgi membrane] (Homo sapiens)
        
        ASAP1 dimer: ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        CNG tetramer [Golgi membrane] (Homo sapiens)
      - ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex (Homo sapiens)
        
        ASAP1 dimer: ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        CNG tetramer [Golgi membrane] (Homo sapiens)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        ASAP1 dimer: ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        CNG tetramer [Golgi membrane] (Homo sapiens)
      - ASAP1 stimulates GTPase activity of ARF4 (Homo sapiens)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        ASAP1 dimer: ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        CNG tetramer [Golgi membrane] (Homo sapiens)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        CNG tetramer [Golgi membrane] (Homo sapiens)
      - Cargo-carrying vesicles bud from the TGN (Homo sapiens)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        CNG tetramer [Golgi membrane] (Homo sapiens)
      - RAB3IP and RAB8A bind to the ciliary targeting complex (Homo sapiens)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        CNG tetramer [Golgi membrane] (Homo sapiens)
        
        RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        CNG tetramer [Golgi membrane] (Homo sapiens)
      - RAB3IP stimulates nucleotide exchange on RAB8A (Homo sapiens)
        
        RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        CNG tetramer [Golgi membrane] (Homo sapiens)
        
        RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
        
        CNG tetramer [Golgi membrane] (Homo sapiens)

Literature References

PubMed ID	Title	Journal	Year
16782012	Ciliary targeting of olfactory CNG channels requires the CNGB1b subunit and the kinesin-2 motor protein, KIF17 Zhang, L, Hurd, TW, Martens, JR, Brown, RL, Jenkins, PM, Verhey, KJ, McEwen, DP, Margolis, B	Curr. Biol.	2006

Participants

components

Participates

as a candidate of

VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)

Inferred To

CNG tetramer [Golgi membrane] (Bos taurus)

CNG tetramer [Golgi membrane] (Caenorhabditis elegans)

CNG tetramer [Golgi membrane] (Canis familiaris)

CNG tetramer [Golgi membrane] (Drosophila melanogaster)

CNG tetramer [Golgi membrane] (Mus musculus)

CNG tetramer [Golgi membrane] (Rattus norvegicus)

CNG tetramer [Golgi membrane] (Sus scrofa)