RDH13 reduces atRAL to atROL

Stable Identifier
R-HSA-5623643
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Multiple reductases may contribute to the reduction of all-trans-retinal (atRAL) to all-trans-retinol (atROL). Human retinol dehydrogenase 13 (RDH13) is located on the outer surface of the mitochondrial inner membrane where it is thought to protect mitochondria against oxidative stress associated with the highly reactive retinaldehyde (Belyaeva et al. 2008).

Literature References
PubMed ID Title Journal Year
18039331 Human retinol dehydrogenase 13 (RDH13) is a mitochondrial short-chain dehydrogenase/reductase with a retinaldehyde reductase activity

Belyaeva, OV, Korkina, OV, Stetsenko, AV, Kedishvili, NY

FEBS J. 2008
Participants
Participates
Catalyst Activity

NADP-retinol dehydrogenase activity of RDH13 [mitochondrial inner membrane]

Orthologous Events
Cross References
Rhea
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