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RDHE2 [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-5621649
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
SDR16C5, Epidermal retinol dehydrogenase 2, RDHE2_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
Signaling by Retinoic Acid (Homo sapiens)
RA biosynthesis pathway (Homo sapiens)
RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Homo sapiens)
RDH10,16,DHRS9,RDHE2 [endoplasmic reticulum membrane] (Homo sapiens)
RDHE2 [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8N3Y7 SDR16C5
Gene Names
SDR16C5, RDHE2
Chain
chain:1-309
Reference Genes
BioGPS Gene:195814 SDR16C5
COSMIC (genes):SDR16C5 SDR16C5
CTD Gene:195814 SDR16C5
dbSNP Gene:195814 SDR16C5
ENSEMBL:ENSG00000170786 SDR16C5
ENSEMBL_homo_sapiens_GENE:ENSG00000170786.13 SDR16C5
HGNC:30311 SDR16C5
KEGG Gene (Homo sapiens):195814 SDR16C5
Monarch:195814 SDR16C5
NCBI Gene:195814 SDR16C5
OMIM:608989 SDR16C5
UCSC:Q8N3Y7 SDR16C5
Reference Transcript
RefSeq:NM_001318050.1 SDR16C5
RefSeq:NM_001318049.1 SDR16C5
RefSeq:NM_138969.3 SDR16C5
Other Identifiers
11734046_a_at
11734047_s_at
11747029_a_at
11754879_a_at
17077341
195814
238017_PM_at
238017_at
3136228
3136230
3136231
3136232
3136233
3136234
3136235
3136238
3136239
3136240
3136242
3136244
3136245
3136251
3136252
80238_at
8150889
85305_at
A_23_P257457
A_24_P317708
GE79214
GO:0000122
GO:0000785
GO:0003714
GO:0003824
GO:0004745
GO:0005515
GO:0005634
GO:0005694
GO:0005783
GO:0005789
GO:0005811
GO:0005886
GO:0006325
GO:0006351
GO:0006355
GO:0006629
GO:0016020
GO:0016491
GO:0017053
GO:0042572
GO:0042574
GO:0043226
GO:0043616
GO:0045814
GO:0061629
GO:0140110
GO:0140297
HMNXSV003036301
HMNXSV003054632
Hs.170673.0.A1_3p_at
ILMN_1710064
PH_hs_0010206
TC08001232.hg
Participates
as a member of
RDH10,16,DHRS9,RDHE2 [endoplasmic reticulum membrane] (Homo sapiens)
Inferred To
Ldsdh1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
RDHE2 [endoplasmic reticulum membrane]
(Gallus gallus)
RDHE2 [endoplasmic reticulum membrane]
(Mus musculus)
RDHE2 [endoplasmic reticulum membrane]
(Saccharomyces cerevisiae)
dhs-3 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
dhs-4 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Sdr16c5 [endoplasmic reticulum membrane]
(Rattus norvegicus)
dhs-29 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Dmel\CG9265 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Dmel\CG15629 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
SDR16C5 [endoplasmic reticulum membrane]
(Bos taurus)
SDR16C5 [endoplasmic reticulum membrane]
(Canis familiaris)
SDR16C5 [endoplasmic reticulum membrane]
(Sus scrofa)
sdr16c5 [endoplasmic reticulum membrane]
(Xenopus tropicalis)
Homologues of RDHE2 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Homologues of RDHE2 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Homologues of RDHE2 [endoplasmic reticulum membrane]
(Saccharomyces cerevisiae)
dhs-19 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
firl [endoplasmic reticulum membrane]
(Drosophila melanogaster)
sdr16c5b [endoplasmic reticulum membrane]
(Danio rerio)
Cross References
RefSeq
NP_001304979.1
,
NP_001304978.1
,
NP_620419.2
OpenTargets
ENSG00000170786
IntEnz
1.1.1.105
HPA
ENSG00000170786-SDR16C5
GeneCards
Q8N3Y7
Ensembl
ENSP00000379947
,
ENST00000396721
,
ENST00000303749
,
ENSG00000170786
,
ENSP00000307607
PRO
Q8N3Y7
Pharos - Targets
Q8N3Y7
HMDB Protein
HMDBP11906
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q05329 GAD2
2
PXLP-K396-GAD2 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
(R-HSA-888582)
PXLP-K396-GAD2 [plasma membrane]
(R-HSA-936509)
0.556
3
UniProt:Q08426 EHHADH
2
EHHADH [peroxisomal matrix]
(R-HSA-400155)
EHHADH [cytosol]
(R-HSA-9033147)
0.556
3
UniProt:P49638 TTPA
1
TTPA [cytosol]
(R-HSA-2980979)
0.556
3
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