HOXB4 gene is transcribed

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R-HSA-5617867
Type
Reaction [omitted]
Species
Homo sapiens
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The HOXB4 gene is transcribed to yield mRNA (in embryos in Giampaolo et al. 1989, in carcinoma cells in Simeone et al. 1990). The microRNA miR-23a binds the 3' untranslated region of HOXB4 mRNA (Koller et al 2013). In mouse embryos Hoxb4 mRNA is observed in rhombomere 7, paraxial mesoderm of somite 7, and caudally.

Literature References
PubMed ID Title Journal Year
23630040 Identification of the transcription factor HOXB4 as a novel target of miR-23a

Koller, K, Das, S, Leuschner, I, Korbelius, M, Hoefler, G, Guertl, B

Genes Chromosomes Cancer 2013
2570724 Differential expression of human HOX-2 genes along the anterior-posterior axis in embryonic central nervous system

Giampaolo, A, Acampora, D, Zappavigna, V, Pannese, M, D'Esposito, M, Carè, A, Faiella, A, Stornaiuolo, A, Russo, G, Simeone, A

Differentiation 1989
1975088 Sequential activation of HOX2 homeobox genes by retinoic acid in human embryonal carcinoma cells

Simeone, A, Acampora, D, Arcioni, L, Andrews, PW, Boncinelli, E, Mavilio, F

Nature 1990
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