HOXB3 mRNA is translated

Stable Identifier
Reaction [omitted]
Homo sapiens
Locations in the PathwayBrowser
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

HOXB3 mRNA is translated to yield HOXB3 protein (Palakurthy et al. 2009, Li et al. 2012, Chen et al. 2013). Translation is repressed by the microRNAs miR-7 and miR-218 (Li et al. 2012) and miR-10A (Weiss et al. 2009).

Literature References
PubMed ID Title Journal Year
19747919 Retinoic acid receptor antagonists inhibit miR-10a expression and block metastatic behavior of pancreatic cancer

Marques, IJ, Woltering, JM, Bagowski, CP, Aghdassi, A, Weiss, FU, Partecke, LI, Heidecke, CD, Lerch, MM, Vlecken, DH

Gastroenterology 2009
22705304 miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer

Zhu, F, Li, Q, Chen, P

Biochem. Biophys. Res. Commun. 2012
19854132 Epigenetic silencing of the RASSF1A tumor suppressor gene through HOXB3-mediated induction of DNMT3B expression

Gobeil, S, Wajapeyee, N, Gazin, C, Santra, MK, Green, MR, Palakurthy, RK, Lin, L

Mol. Cell 2009
23219899 HoxB3 promotes prostate cancer cell progression by transactivating CDCA3

Shang, Z, Jiang, N, Niu, Y, Quan, C, Zhu, S, Chen, J

Cancer Lett. 2013
Inferred From
Cite Us!