Reactome | IFT80 [cilium]

IFT80 [cilium]

Stable Identifier

R-HSA-5617613

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cilium

Synonyms

IFT-B 80, IFT B, WDR56

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9P2H3 IFT80

Gene Names

IFT80, KIAA1374, WDR56

Chain

chain:1-777

Reference Genes

BioGPS Gene:57560 IFT80

COSMIC (genes):IFT80 IFT80

CTD Gene:57560 IFT80

dbSNP Gene:57560 IFT80

ENSEMBL:ENSG00000068885 IFT80

HGNC:29262 IFT80

Monarch:57560 IFT80

NCBI Gene:57560 IFT80

OMIM:611177 IFT80

UCSC:Q9P2H3 IFT80

Reference Transcript

Other Identifiers

11732396_a_at

11732397_a_at

1558956_PM_s_at

1558956_s_at

1564231_PM_at

1564231_at

16960963

226098_PM_at

226098_at

2703140

2703141

2703142

2703143

2703144

2703145

2703146

2703147

2703149

2703152

2703153

2703157

2703158

2703159

2703160

2703161

2703162

2703163

2703167

2703168

2703170

2703172

2703173

2703174

2703176

2703177

2703178

2703180

2703181

2703183

2703184

2703185

2703186

2703187

2703189

2703190

49323_at

57560

78135_at

8091737

A_23_P316150

A_23_P406013

A_24_P255645

GE85516

GO:0001501

GO:0001649

GO:0001958

GO:0002062

GO:0003417

GO:0003418

GO:0005515

GO:0005737

GO:0005813

GO:0005815

GO:0005856

GO:0005929

GO:0007018

GO:0007163

GO:0007224

GO:0008543

GO:0010839

GO:0030154

GO:0030992

GO:0033687

GO:0035264

GO:0035567

GO:0035630

GO:0035720

GO:0036064

GO:0042476

GO:0043226

GO:0043491

GO:0043616

GO:0044691

GO:0044782

GO:0048856

GO:0048863

GO:0060173

GO:0060271

GO:0060349

GO:0061975

GO:0071895

GO:0072089

GO:0097500

GO:0097542

GO:0097731

GO:1905515

GO:2000051

HMNXSV003045955

Hs.186547.0.A1_3p_at

Hs2.407402.1.A1_3p_s_at

ILMN_1760617

ILMN_2156115

PH_hs_0010922

TC03003398.hg

Participates

as an input of

Assembly of IFT B complex (Homo sapiens)

as a component of

IFT B* [cilium] (Homo sapiens)

Other forms of this molecule

IFT80 [ciliary tip]

Inferred To

che-2 [cilium] (Caenorhabditis elegans)

IFT80 [cilium] (Bos taurus)

IFT80 [cilium] (Canis familiaris)

IFT80 [cilium] (Gallus gallus)

IFT80 [cilium] (Sus scrofa)

Ift80 [cilium] (Mus musculus)

Ift80 [cilium] (Rattus norvegicus)

Cross References

ENSEMBL

ENST00000326448, ENSP00000418196, ENST00000496589, ENSP00000420646, ENST00000483465, ENSP00000312778

OpenTargets

ENSG00000068885

HPA

ENSG00000068885-IFT80

PRO

Q9P2H3

Pharos - Targets

Q9P2H3

Orphanet

IFT80

Interactors (18)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q86WT1 IFT70A	2	TTC30A [ciliary tip] (R-HSA-5637966) TTC30A [cilium] (R-HSA-5637968)	0.725	6
UniProt:Q8N4P2 IFT70B	2	TTC30B [ciliary tip] (R-HSA-5637970) TTC30B [cilium] (R-HSA-5637971)	0.725	5
UniProt:Q9NWB7 IFT57	2	IFT57 [cilium] (R-HSA-5610389) IFT57 [ciliary tip] (R-HSA-5625363)	0.725	7
UniProt:Q9BW83 IFT27	2	IFT27 [ciliary tip] (R-HSA-5625357) IFT27 [cilium] (R-HSA-5617621)	0.69	7
UniProt:Q13099 IFT88	8	PolyUb-Misfolded IFT88 [lysosomal lumen] (R-HSA-9660026) PolyUb-Misfolded IFT88 [cytosol] (R-HSA-9641125) Ub-Misfolded IFT88 [cytosol] (R-HSA-9641114) Misfolded IFT88 [cytosol] (R-HSA-9640115) Misfolded IFT88 [cilium] (R-HSA-9640106) IFT88 [cilium] (R-HSA-5610385) PolyUb-Misfolded IFT88 [late endosome lumen] (R-HSA-9660031) IFT88 [ciliary tip] (R-HSA-5625371)	0.643	8
UniProt:Q9H7X7 IFT22	2	RABL5 [cilium] (R-HSA-5617605) RABL5 [ciliary tip] (R-HSA-5625388)	0.638	5
UniProt:Q9NQC8 IFT46	2	IFT46 [ciliary tip] (R-HSA-5625359) IFT46 [cilium] (R-HSA-5617617)	0.638	5
UniProt:Q9UG01 IFT172	2	IFT172 [ciliary tip] (R-HSA-5625353) IFT172 [cilium] (R-HSA-5610383)	0.592	6
UniProt:P31146 CORO1A	1	CORO1A [cytosol] (R-HSA-9636432)	0.527	2
UniProt:Q8TDR0 TRAF3IP1	2	TRAF3IP1 [ciliary tip] (R-HSA-5625404) TRAF3IP1 [cilium] (R-HSA-5617603)	0.508	3
UniProt:Q8WYA0 IFT81	2	IFT81 [cilium] (R-HSA-5617769) IFT81 [ciliary tip] (R-HSA-5625369)	0.508	3
UniProt:Q9Y547 HSPB11	2	HSPB11 [ciliary tip] (R-HSA-5625342) HSPB11 [cilium] (R-HSA-5617628)	0.508	2
UniProt:Q9Y266 NUDC	4	NUDC [cytosol] (R-HSA-377731) NUDC [nucleoplasm] (R-HSA-156716) p-S274,S326-NUDC [cytosol] (R-HSA-156702) p-S274,S326-NUDC [spindle] (R-HSA-9648125)	0.508	3
UniProt:Q9Y366 IFT52	2	IFT52 [ciliary tip] (R-HSA-5625360) IFT52 [cilium] (R-HSA-5610387)	0.508	2
UniProt:A0AVF1 TTC26	2	TTC26 [ciliary tip] (R-HSA-5637962) TTC26 [cilium] (R-HSA-5637963)	0.508	3
UniProt:Q96AJ1 CLUAP1	2	CLUAP [ciliary tip] (R-HSA-5637957) CLUAP [cilium] (R-HSA-5637960)	0.508	3
UniProt:Q96LB3 IFT74	2	IFT74 [ciliary tip] (R-HSA-5625364) IFT74 [cilium] (R-HSA-5617616)	0.508	4
UniProt:Q8IY31 IFT20	3	IFT20 [ciliary tip] (R-HSA-5625355) IFT20 [Golgi membrane] (R-HSA-5617625) IFT20 [cilium] (R-HSA-5617624)	0.508	3

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