HOXA1 mRNA is translated

Stable Identifier
Reaction [omitted]
Homo sapiens
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The HOXA1 mRNA is translated to yield HOXA1 protein (Chen et al. 2013, Chen et al. 2014). MicroRNAs miR-10a (Garzon et al. 2006), let-7c (Zhan et al. 2013), miR-99 (Chen et al. 2013) and miR-100 (Chen et al. 2014) negatively regulate translation in adult cells, however their roles in embryonic cells are unknown.
Literature References
PubMed ID Title Journal Year
23534758 Let-7c inhibits NSCLC cell proliferation by targeting HOXA1

Yu, J, Qu, Q, Wang, G, Tan, SL, Lou, XY, Liu, YZ, Zhou, HH, Zhan, M

Asian Pac. J. Cancer Prev. 2013
24312487 MicroRNA-99 family members suppress Homeobox A1 expression in epithelial cells

Adjei, BS, Zhang, L, Wang, A, Jin, Y, Chen, Z, Chen, D, Dragas, D, Zhou, X, Dai, Y

PLoS ONE 2013
16549775 MicroRNA fingerprints during human megakaryocytopoiesis

Iuliano, R, Aqeilan, RI, Croce, CM, Cimmino, A, Garzon, R, Calin, GA, Andreeff, M, Liu, CG, Palumbo, T, Marcucci, G, Bhatt, D, Alder, H, Volinia, S, Pichiorri, F, Bloomfield, CD

Proc. Natl. Acad. Sci. U.S.A. 2006
24586203 miR-100 induces epithelial-mesenchymal transition but suppresses tumorigenesis, migration and invasion

Yuan, Y, Liang, H, Gupta, S, Sun, Y, Wang, M, Zhang, P, Teruya-Feldstein, J, Zhang, J, Ma, L, Han, Z, Chen, D, You, MJ, Hung, MC

PLoS Genet. 2014
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