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p-S23,S24-TNNI3 [cytosol]
Stable Identifier
R-HSA-5617219
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Troponin I, cardiac muscle, TNNI3_HUMAN
Locations in the PathwayBrowser
Expand all
Muscle contraction (Homo sapiens)
Cardiac conduction (Homo sapiens)
Ion homeostasis (Homo sapiens)
PRKACA phosphorylates TNNI3 (Homo sapiens)
p-S23,S24-TNNI3 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P19429 TNNI3
Gene Names
TNNI3, TNNC1
Chain
initiator methionine:, chain:2-210
Reference Genes
BioGPS Gene:7137 TNNI3
COSMIC (genes):TNNC1 TNNI3
COSMIC (genes):TNNI3 TNNI3
CTD Gene:7137 TNNI3
dbSNP Gene:7137 TNNI3
ENSEMBL:ENSG00000129991 TNNI3
HGNC:11947 TNNI3
Monarch:7137 TNNI3
NCBI Gene:7137 TNNI3
OMIM:191044 TNNI3
UCSC:P19429 TNNI3
Reference Transcript
RefSeq:NM_000363.4 TNNI3
Other Identifiers
11722648_a_at
16875612
205742_PM_at
205742_at
36477_at
3871128
3871129
3871130
3871131
3871132
3871133
3871134
3871135
3871136
3871137
3871138
3871139
3871140
3871141
7137
8039353
A_23_P67453
GE80910
GE87542
GO:0001570
GO:0001980
GO:0003009
GO:0003012
GO:0003013
GO:0003779
GO:0005515
GO:0005737
GO:0005829
GO:0005861
GO:0006874
GO:0006937
GO:0006940
GO:0006941
GO:0007507
GO:0008092
GO:0010882
GO:0019855
GO:0019901
GO:0019904
GO:0030016
GO:0030017
GO:0030154
GO:0030172
GO:0031014
GO:0032780
GO:0043226
GO:0043292
GO:0048306
GO:0048856
GO:0050877
GO:0051015
GO:0055010
GO:0060047
GO:0060048
GO:0097512
GO:0098772
GO:1990584
HMNXSV003011601
PH_hs_0028634
PH_hs_0034354
TC19001859.hg
X90780_rna1_at
g4507622_3p_at
Participates
as an output of
PRKACA phosphorylates TNNI3 (Homo sapiens)
Other forms of this molecule
TNNI3 [cytosol]
Inferred To
phospho-tnni1c [cytosol]
(Danio rerio)
phospho-tnni3 [cytosol]
(Xenopus tropicalis)
phospho-p-S23,S24-TNNI3 [cytosol]
(Sus scrofa)
phospho-tnni1d [cytosol]
(Danio rerio)
phospho-tni-4 [cytosol]
(Caenorhabditis elegans)
phospho-wupA [cytosol]
(Drosophila melanogaster)
phospho-TNNI3 [cytosol]
(Canis familiaris)
phospho-tni-3 [cytosol]
(Caenorhabditis elegans)
phospho-Tnni3 [cytosol]
(Mus musculus)
phospho-Tnni3 [cytosol]
(Rattus norvegicus)
phospho-tni-1 [cytosol]
(Caenorhabditis elegans)
Homologues of p-S23,S24-TNNI3 [cytosol]
(Caenorhabditis elegans)
Homologues of p-S23,S24-TNNI3 [cytosol]
(Danio rerio)
phospho-unc-27 [cytosol]
(Caenorhabditis elegans)
phospho-tnni1b [cytosol]
(Danio rerio)
Modified Residues
Name
O-phospho-L-serine at 23
Coordinate
23
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 24
Coordinate
24
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
OpenTargets
ENSG00000129991
ENSEMBL
ENST00000344887
,
ENSP00000341838
HPA
ENSG00000129991-TNNI3
PRO
P19429
Pharos - Targets
P19429
Orphanet
TNNI3
GlyGen
P19429
HMDB Protein
HMDBP08061
PDB
7SWI
,
2N7L
,
7SWG
,
2MZP
,
4Y99
,
7UHA
,
8FMT
,
8FMN
,
7SC3
,
2KRD
,
7JGI
,
2L1R
,
7SUP
,
8FMQ
,
8FMO
,
1MXL
,
7SXD
,
7UTI
,
8FMR
,
7SVC
,
8FMP
,
2KGB
,
5WCL
,
1OZS
,
8FMM
,
7UTL
,
8DZV
,
8FMS
,
7UH9
,
7SC2
,
6KN7
,
6KN8
,
1J1E
,
1J1D
,
1LXF
,
7SXC
,
6MV3
,
5VLN
,
5W88
Interactors (9)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P63316 TNNC1
1
TNNC1 [cytosol]
(R-HSA-390533)
0.674
5
UniProt:P05014 IFNA4
1
IFNA4 [extracellular region]
(R-HSA-877342)
0.589
2
UniProt:O76024 WFS1
3
WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956747)
p-WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956998)
WFS1 [endoplasmic reticulum membrane]
(R-HSA-535474)
0.556
3
UniProt:A6NK89 RASFA
0.556
3
UniProt:O43933 PEX1
1
PEX1 [cytosol]
(R-HSA-9033116)
0.556
3
UniProt:P02585 TNNC2
1
TNNC2 [cytosol]
(R-HSA-390531)
0.556
3
UniProt:Q9UKA8-1 RCAN3
0.527
3
UniProt:Q9UKA8-4 RCAN3
0.527
2
UniProt:Q59H18 TNI3K
0.508
2
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