Glycosyltransferase-like protein LARGE2 (GYLTL1B) is a bifunctional glycosyltransferases with both xylosyltransferase and beta-1,3-glucuronyltransferase activities which can form polymeric Xyl-GlcA repeats. GYLTL1B is involved in the physiological function of alpha-dystroglycan (DAG1) which plays a key role in skeletal muscle function and regeneration (Inamori et al. 2013, Wells 2013, Inamori et al. 2014).
Inamori, K, Yoshida-Moriguchi, T, Zhu, Z, Willer, T, Anderson, ME, Hara, Y, Campbell, KP
Inamori, K, Moore, SA, Bönnemann, CG, Clarke, NF, Willer, T, Guicheney, P, Anderson, ME, Hara, Y, Campbell, KP, Venzke, D
Wells, L
glucuronosyltransferase activity of B4GAT1:GYLTL1B [Golgi membrane]
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