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NLRC3 [cytosol]
Stable Identifier
R-HSA-561197
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Protein NLRC3, NLRC3_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q9ULZ3 PYCARD
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Cytosolic sensors of pathogen-associated DNA (Homo sapiens)
STING mediated induction of host immune responses (Homo sapiens)
IRF3-mediated induction of type I IFN (Homo sapiens)
STING recruits TBK1 and IRF3 (Homo sapiens)
NLRC3 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q7RTR2 NLRC3
Gene Names
NLRC3, NOD3
Chain
chain:1-1065
Reference Genes
BioGPS Gene:197358 NLRC3
COSMIC (genes):NLRC3 NLRC3
CTD Gene:197358 NLRC3
dbSNP Gene:197358 NLRC3
ENSEMBL:ENSG00000167984 NLRC3
ENSEMBL_homo_sapiens_GENE:ENSG00000167984.18 NLRC3
HGNC:29889 NLRC3
KEGG Gene (Homo sapiens):197358 NLRC3
Monarch:197358 NLRC3
NCBI Gene:197358 NLRC3
OMIM:615648 NLRC3
UCSC:Q7RTR2 NLRC3
Reference Transcript
RefSeq:NM_178844.3 NLRC3
Other Identifiers
11730109_a_at
16823365
197358
236295_PM_s_at
236295_s_at
3677658
3677659
3677660
3677661
3677663
3677664
3677665
3677666
3677667
3677668
3677669
3677670
3677671
3677672
3677673
3677675
3677676
3677677
3677678
3677679
3677680
3677684
3677685
3677686
3677688
3677689
3677690
3677692
3677693
3677695
3677696
3677697
3677700
3677701
77360_at
7998983
A_23_P329399
A_23_P340019
A_24_P169937
GO:0000166
GO:0002376
GO:0003674
GO:0005515
GO:0005524
GO:0005737
GO:0005815
GO:0005829
GO:0005856
GO:0006351
GO:0006355
GO:0006954
GO:0007249
GO:0023052
GO:0032088
GO:0032687
GO:0032688
GO:0032715
GO:0032720
GO:0034451
GO:0035556
GO:0036312
GO:0042110
GO:0043124
GO:0043226
GO:0043231
GO:0045824
GO:0048147
GO:0048471
GO:0050680
GO:0050728
GO:0051898
GO:0065003
GO:0098542
GO:1900016
GO:1900226
GO:1901223
HMNXSV003030261
Hs.145668.1.A1_3p_at
ILMN_1740576
PH_hs_0007418
TC16000820.hg
This entity regulates
Negatively
STING recruits TBK1 and IRF3
(Homo sapiens)
Cross References
RefSeq
NP_849172.2
Guide to Pharmacology - Targets
1764
OpenTargets
ENSG00000167984
HPA
ENSG00000167984-NLRC3
GeneCards
Q7RTR2
Ensembl
ENSP00000352039
,
ENST00000359128
,
ENST00000615877
,
ENSG00000167984
,
ENSP00000482989
PRO
Q7RTR2
Pharos - Targets
Q7RTR2
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9ULZ3 PYCARD
4
PYCARD [cytosol]
(R-HSA-561191)
PYCARD [azurophil granule lumen]
(R-HSA-6798768)
PYCARD [extracellular region]
(R-HSA-6806196)
PYCARD [secretory granule lumen]
(R-HSA-6800957)
0.556
3
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