PYCARD [cytosol]

Stable Identifier
R-HSA-561191
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
ASC, Apoptosis-associated speck-like protein containing a CARD, ASC_HUMAN
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q9ULZ3 PYCARD
Gene Names
PYCARD, ASC, CARD5, TMS1
Chain
chain:1-195
Reference Genes
BioGPS Gene:29108 PYCARD
COSMIC (genes):PYCARD PYCARD
CTD Gene:29108 PYCARD
dbSNP Gene:29108 PYCARD
ENSEMBL:ENSG00000103490 PYCARD
HGNC:16608 PYCARD
KEGG Gene (Homo sapiens):29108 PYCARD
Monarch:29108 PYCARD
NCBI Gene:29108 PYCARD
OMIM:606838 PYCARD
UCSC:Q9ULZ3 PYCARD
Reference Transcript
Other Identifiers
0000050195
11721169_a_at
11750531_a_at
16825997
221666_PM_s_at
221666_s_at
29108
3688312
3688313
3688314
3688315
3688317
3688318
3688319
3688320
46664_at
8001030
A_23_P26629
GE58507
GO:0000139
GO:0001773
GO:0002020
GO:0002218
GO:0002221
GO:0002230
GO:0002277
GO:0002376
GO:0002588
GO:0002821
GO:0003674
GO:0004197
GO:0005138
GO:0005515
GO:0005523
GO:0005575
GO:0005576
GO:0005622
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005739
GO:0005764
GO:0005773
GO:0005783
GO:0005794
GO:0005829
GO:0005856
GO:0005874
GO:0006464
GO:0006508
GO:0006810
GO:0006914
GO:0006915
GO:0006919
GO:0006950
GO:0006954
GO:0007005
GO:0007010
GO:0007155
GO:0007165
GO:0007231
GO:0008092
GO:0008150
GO:0008219
GO:0008233
GO:0008283
GO:0008385
GO:0008656
GO:0009056
GO:0009058
GO:0009617
GO:0010506
GO:0010803
GO:0016020
GO:0016192
GO:0017024
GO:0019899
GO:0022607
GO:0030234
GO:0030838
GO:0031410
GO:0031647
GO:0032088
GO:0032090
GO:0032688
GO:0032722
GO:0032729
GO:0032731
GO:0032733
GO:0032755
GO:0032757
GO:0032760
GO:0032991
GO:0033209
GO:0034641
GO:0034774
GO:0035578
GO:0040011
GO:0042104
GO:0042771
GO:0042802
GO:0042803
GO:0042981
GO:0043025
GO:0043065
GO:0043087
GO:0043124
GO:0043226
GO:0043280
GO:0043281
GO:0044281
GO:0044325
GO:0044351
GO:0045087
GO:0046330
GO:0046456
GO:0046983
GO:0048870
GO:0050727
GO:0050729
GO:0050766
GO:0050829
GO:0050830
GO:0050870
GO:0051091
GO:0051092
GO:0051260
GO:0051604
GO:0051607
GO:0061702
GO:0065003
GO:0070269
GO:0070374
GO:0070700
GO:0071222
GO:0071347
GO:0071356
GO:0071901
GO:0072332
GO:0072558
GO:0072559
GO:0090200
GO:0097153
GO:0097169
GO:0097202
GO:1900016
GO:2000406
GO:2001056
GO:2001238
GO:2001242
HMNXSV003043000
ILMN_1698766
ILMN_2398274
PH_hs_0022963
TC16001052.hg
g13325315_3p_a_at
Participates
as a component of
as an input of
Other forms of this molecule
PYCARD [secretory granule lumen]
PYCARD [extracellular region]
PYCARD [azurophil granule lumen]
Inferred To
Pycard [cytosol] (Mus musculus)
Pycard [cytosol] (Rattus norvegicus)
PYCARD [cytosol] (Bos taurus)
PYCARD [cytosol] (Canis familiaris)
CARD8 [cytosol] (Gallus gallus)
pycard [cytosol] (Danio rerio)
ASC [cytosol] (Sus scrofa)
Cross References
RefSeq
OpenTargets
HPA
GeneCards
Ensembl
PRO
Pharos - Targets
Orphanet
HMDB Protein
PDB
Interactors (15)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q96P20 NLRP3  2 0.917 24
 UniProt:O14862 AIM2  1 0.892 13
 UniProt:O15553 MEFV  1 0.796 10
 UniProt:Q9ULZ3 PYCARD  4 0.789 8
 UniProt:P29466 CASP1  5 0.765 9
 UniProt:Q07812 BAX  3 0.619 7
 UniProt:Q56P42 PYDC2      0.602 4
 UniProt:P43405 SYK  6 0.591 4
 UniProt:Q9C000 NLRP1  1 0.558 5
 UniProt:O00471 EXOC5  2 0.556 5
 UniProt:Q7RTR2 NLRC3  1 0.556 3
 UniProt:Q9NPP4 NLRC4  1 0.547 2
 UniProt:O15111 CHUK  3 0.512 5
 UniProt:O14920 IKBKB  3 0.512 4
 UniProt:Q8WXC3 PYDC1      0.463 2
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