PYCARD [cytosol]

Stable Identifier
R-HSA-561191
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
ASC, Apoptosis-associated speck-like protein containing a CARD, ASC_HUMAN
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q9ULZ3 PYCARD
Gene Names
PYCARD, ASC, CARD5, TMS1
Chain
chain:1-195
Reference Genes
BioGPS Gene:29108 PYCARD
COSMIC (genes):PYCARD PYCARD
CTD Gene:29108 PYCARD
dbSNP Gene:29108 PYCARD
ENSEMBL:ENSG00000103490 PYCARD
ENSEMBL_homo_sapiens_GENE:ENSG00000103490 PYCARD
HGNC:16608 PYCARD
KEGG Gene (Homo sapiens):29108 PYCARD
Monarch:29108 PYCARD
NCBI Gene:29108 PYCARD
OMIM:606838 PYCARD
UCSC:Q9ULZ3 PYCARD
Reference Transcript
Other Identifiers
0000050195
11721169_a_at
11750531_a_at
15948
16825997
1UCP
221666_s_at
29108
2KN6
3688312
3688313
3688314
3688315
3688317
3688318
3688319
3688320
3688321
3J63
46664_at
49074
54496
5H8O
6853
8001030
A_23_P26629
AAF99665
AAG01187
AAG01188
AAG30286
AAH04470
AAH13569
AAK63850
BAA87339
BAA91012
CAB006853
CAB015948
CCDS10708
CCDS10709
ENSG00000103490
ENSP00000247470
ENSP00000340441
ENST00000247470
ENST00000350605
EntrezGene:29108
g13325315_3p_a_at
GE58507
GO:0001773
GO:0002020
GO:0002218
GO:0002230
GO:0002277
GO:0002376
GO:0002588
GO:0002821
GO:0003674
GO:0005138
GO:0005515
GO:0005523
GO:0005575
GO:0005576
GO:0005622
GO:0005623
GO:0005634
GO:0005730
GO:0005737
GO:0005739
GO:0005764
GO:0005773
GO:0005783
GO:0005829
GO:0006464
GO:0006810
GO:0006914
GO:0006915
GO:0006919
GO:0006950
GO:0006954
GO:0007005
GO:0007010
GO:0007155
GO:0007165
GO:0008092
GO:0008150
GO:0008219
GO:0008233
GO:0008283
GO:0008385
GO:0008630
GO:0008656
GO:0009056
GO:0009058
GO:0009617
GO:0010506
GO:0010803
GO:0016192
GO:0017024
GO:0019899
GO:0022607
GO:0030234
GO:0030838
GO:0031410
GO:0031647
GO:0032088
GO:0032090
GO:0032611
GO:0032688
GO:0032729
GO:0032755
GO:0032760
GO:0032991
GO:0033209
GO:0034641
GO:0034774
GO:0035578
GO:0040011
GO:0042104
GO:0042771
GO:0042802
GO:0042803
GO:0042981
GO:0043025
GO:0043065
GO:0043087
GO:0043124
GO:0043226
GO:0043280
GO:0043281
GO:0043312
GO:0044325
GO:0044351
GO:0045087
GO:0046330
GO:0046983
GO:0048870
GO:0050718
GO:0050727
GO:0050766
GO:0050829
GO:0050870
GO:0051091
GO:0051092
GO:0051604
GO:0051607
GO:0065003
GO:0070374
GO:0070700
GO:0071222
GO:0071347
GO:0071356
GO:0071901
GO:0072332
GO:0072558
GO:0072559
GO:0090197
GO:0090200
GO:0097153
GO:0097169
GO:0097202
GO:2000406
GO:2000484
GO:2000778
GO:2001056
GO:2001181
GO:2001238
GO:2001242
H3BP42
HGNC:16608
HPA049074
HPA054496
ILMN_1698766
ILMN_2398274
IPR001315
IPR004020
IPR011029
IPR033516
MIM:606838
NM_013258
NM_145182
NP_037390
NP_660183
PF00619
PF02758
PH_hs_0022963
PYCARD
PYCARD-201
PYCARD-202
SM01289
TC16001052.hg
uc002ebm.4
uc010cak.4
UPI000002A408
UPI0000032BA7
Participant Of
input
hasComponent
Other forms of this molecule
PYCARD [secretory granule lumen]
PYCARD [extracellular region]
PYCARD [azurophil granule lumen]
Inferred To
PYCARD [cytosol] (Bos taurus)
PYCARD [cytosol] (Canis familiaris)
PYCARD [cytosol] (Danio rerio)
PYCARD [cytosol] (Mus musculus)
PYCARD [cytosol] (Rattus norvegicus)
PYCARD [cytosol] (Sus scrofa)
Cross References
RefSeq
OpenTargets
GeneCards
DOCK Blaster
PRO
Orphanet
PDB
Interactors (15)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:O14862 AIM2  1 0.892 13
 UniProt:Q96P20 NLRP3  2 0.81 9
 UniProt:O15553 MEFV  1 0.796 10
 UniProt:Q9ULZ3 PYCARD  4 0.789 8
 UniProt:P29466 CASP1  5 0.765 9
 UniProt:Q07812 BAX  3 0.619 7
 UniProt:Q56P42 PYDC2      0.602 4
 UniProt:P43405 SYK  6 0.591 4
 UniProt:Q9C000 NLRP1  1 0.558 5
 UniProt:O00471 EXOC5  2 0.556 5
 UniProt:Q7RTR2 NLRC3  1 0.556 3
 UniProt:Q9NPP4 NLRC4  1 0.547 2
 UniProt:O15111 CHUK  3 0.512 5
 UniProt:O14920 IKBKB  3 0.512 4
 UniProt:Q8WXC3 PYDC1      0.463 2