PYCARD [cytosol]

Stable Identifier
R-HSA-561191
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
ASC, Apoptosis-associated speck-like protein containing a CARD, ASC_HUMAN
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q9ULZ3 PYCARD
Gene Names
PYCARD, ASC, CARD5, TMS1
Chain
chain:1-195
Reference Genes
BioGPS Gene:29108 PYCARD
COSMIC (genes):PYCARD PYCARD
CTD Gene:29108 PYCARD
dbSNP Gene:29108 PYCARD
ENSEMBL:ENSG00000103490 PYCARD
HGNC:16608 PYCARD
KEGG Gene (Homo sapiens):29108 PYCARD
Monarch:29108 PYCARD
NCBI Gene:29108 PYCARD
OMIM:606838 PYCARD
UCSC:Q9ULZ3 PYCARD
Reference Transcript
Other Identifiers
0000050195
11721169_a_at
11750531_a_at
15948
16825997
1UCP
221666_s_at
29108
2KN6
3688312
3688313
3688314
3688315
3688317
3688318
3688319
3688320
3J63
46664_at
49074
54496
5H8O
6853
6N1H
8001030
A_23_P26629
AAF99665
AAG01187
AAG01188
AAG30286
AAH04470
AAH13569
AAK63850
AB023416
AF184072
AF184073
AF255794
AF310103
AF384665
AK000211
BAA87339
BAA91012
BC004470
BC013569
CAB006853
CAB015948
CCDS10708
CCDS10709
ENSG00000103490
ENSP00000247470
ENSP00000340441
ENST00000247470
ENST00000247470.9
ENST00000350605
ENST00000350605.4
EntrezGene:29108
EntrezGene:PYCARD
g13325315_3p_a_at
GE58507
GO:0000139
GO:0001773
GO:0002020
GO:0002218
GO:0002230
GO:0002277
GO:0002376
GO:0002588
GO:0002821
GO:0003674
GO:0004197
GO:0005138
GO:0005515
GO:0005523
GO:0005575
GO:0005576
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005739
GO:0005764
GO:0005773
GO:0005783
GO:0005794
GO:0005829
GO:0006464
GO:0006508
GO:0006810
GO:0006914
GO:0006915
GO:0006919
GO:0006950
GO:0006954
GO:0007005
GO:0007010
GO:0007155
GO:0007165
GO:0008092
GO:0008150
GO:0008219
GO:0008233
GO:0008283
GO:0008385
GO:0008630
GO:0008656
GO:0009056
GO:0009058
GO:0009617
GO:0010506
GO:0010803
GO:0015031
GO:0016020
GO:0016192
GO:0017024
GO:0019899
GO:0022607
GO:0030234
GO:0030838
GO:0031410
GO:0031647
GO:0032088
GO:0032090
GO:0032611
GO:0032688
GO:0032729
GO:0032731
GO:0032755
GO:0032760
GO:0032991
GO:0033209
GO:0034641
GO:0034774
GO:0035578
GO:0040011
GO:0042104
GO:0042771
GO:0042802
GO:0042803
GO:0042981
GO:0043025
GO:0043065
GO:0043087
GO:0043124
GO:0043226
GO:0043280
GO:0043281
GO:0043312
GO:0044325
GO:0044351
GO:0045087
GO:0046330
GO:0046983
GO:0048870
GO:0050718
GO:0050727
GO:0050766
GO:0050829
GO:0050870
GO:0051091
GO:0051092
GO:0051260
GO:0051604
GO:0051607
GO:0065003
GO:0070374
GO:0070700
GO:0071222
GO:0071347
GO:0071356
GO:0071901
GO:0072332
GO:0072558
GO:0072559
GO:0090197
GO:0090200
GO:0097153
GO:0097169
GO:0097192
GO:0097202
GO:1900016
GO:2000406
GO:2000484
GO:2000778
GO:2001056
GO:2001181
GO:2001238
GO:2001242
H3BP42
HGNC:16608
HPA049074
HPA054496
ILMN_1698766
ILMN_2398274
IPR001315
IPR002398
IPR004020
IPR011029
IPR033516
MIM:606838
NM_013258
NM_145182
NP_037390
NP_660183
PF00619
PF02758
PH_hs_0022963
PYCARD
PYCARD-201
PYCARD-202
SM01289
TC16001052.hg
UPI000002A408
UPI0000032BA7
Participant Of
hasComponent
input
Other forms of this molecule
PYCARD [azurophil granule lumen]
PYCARD [extracellular region]
PYCARD [secretory granule lumen]
Inferred To
Pycard [cytosol] (Mus musculus)
Pycard [cytosol] (Rattus norvegicus)
CASP2 [cytosol] (Gallus gallus)
PYCARD [cytosol] (Bos taurus)
ASC [cytosol] (Sus scrofa)
casp2 [cytosol] (Danio rerio)
casp2 [cytosol] (Xenopus tropicalis)
ced-3 [cytosol] (Caenorhabditis elegans)
Cross References
RefSeq
OpenTargets
GeneCards
HPA
Ensembl
PRO
Orphanet
PDB
Interactors (15)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:O14862 AIM2  1 0.892 13
 UniProt:Q96P20 NLRP3  2 0.86 10
 UniProt:O15553 MEFV  1 0.796 10
 UniProt:Q9ULZ3 PYCARD  4 0.789 8
 UniProt:P29466 CASP1  5 0.765 9
 UniProt:Q07812 BAX  3 0.619 7
 UniProt:Q56P42 PYDC2      0.602 4
 UniProt:P43405 SYK  6 0.591 4
 UniProt:Q9C000 NLRP1  1 0.558 5
 UniProt:Q7RTR2 NLRC3  1 0.556 3
 UniProt:O00471 EXOC5  2 0.556 5
 UniProt:Q9NPP4 NLRC4  1 0.547 2
 UniProt:O15111 CHUK  3 0.512 5
 UniProt:O14920 IKBKB  3 0.512 4
 UniProt:Q8WXC3 PYDC1      0.463 2
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