Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
SLC22A16 [plasma membrane]
Stable Identifier
R-HSA-561104
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
FLIPT2, Fly-like putative transporter 2, Solute carrier family 22 member 16, S22AG_HUMAN
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
Organic cation/anion/zwitterion transport (Homo sapiens)
Organic cation transport (Homo sapiens)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Homo sapiens)
SLC22A4, 5,15,16 [plasma membrane] (Homo sapiens)
SLC22A16 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q86VW1 SLC22A16
Gene Names
SLC22A16, OCT6
Chain
chain:1-577
Reference Genes
BioGPS Gene:85413 SLC22A16
COSMIC (genes):SLC22A16 SLC22A16
CTD Gene:85413 SLC22A16
dbSNP Gene:85413 SLC22A16
ENSEMBL:ENSG00000004809 SLC22A16
ENSEMBL_homo_sapiens_GENE:ENSG00000004809.14 SLC22A16
HGNC:20302 SLC22A16
KEGG Gene (Homo sapiens):85413 SLC22A16
Monarch:85413 SLC22A16
NCBI Gene:85413 SLC22A16
OMIM:608276 SLC22A16
UCSC:Q86VW1 SLC22A16
Reference Transcript
RefSeq:XM_011536205.2 SLC22A16
RefSeq:NM_033125.3 SLC22A16
Other Identifiers
11753084_a_at
11754703_a_at
17022562
232232_PM_s_at
232232_s_at
232233_PM_at
232233_at
2969408
2969409
2969415
2969418
2969420
2969421
2969424
2969426
2969430
2969431
2969432
2969433
2969435
2969436
2969437
2969438
2969439
2969440
2969441
2969442
79327_at
8128850
85413
AC002464_at
A_23_P42004
GE61371
GO:0005215
GO:0005275
GO:0005829
GO:0005886
GO:0006811
GO:0007018
GO:0007283
GO:0007338
GO:0015101
GO:0015226
GO:0015606
GO:0015695
GO:0015837
GO:0015879
GO:0016020
GO:0022414
GO:0022857
GO:0030154
GO:0030317
GO:0046717
GO:0048870
GO:0055085
GO:1902603
GO:1903711
HMNXSV003013777
Hs.191996.0.S1_3p_at
Hs.191996.0.S1_3p_s_at
ILMN_1763609
PH_hs_0011307
TC06002009.hg
Participates
as a member of
SLC22A4, 5,15,16 [plasma membrane] (Homo sapiens)
Inferred To
Orct [plasma membrane]
(Drosophila melanogaster)
Dmel\CG16727 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG14855 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG4630 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG7342 [plasma membrane]
(Drosophila melanogaster)
pes-23 [plasma membrane]
(Caenorhabditis elegans)
Dmel\CG10486 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG6356 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG5592 [plasma membrane]
(Drosophila melanogaster)
CG6596 [plasma membrane]
(Drosophila melanogaster)
CT19169 [plasma membrane]
(Drosophila melanogaster)
CarT [plasma membrane]
(Drosophila melanogaster)
oct-2 [plasma membrane]
(Caenorhabditis elegans)
suex-2 [plasma membrane]
(Caenorhabditis elegans)
CG31530-RA [plasma membrane]
(Drosophila melanogaster)
CG8654-RA [plasma membrane]
(Drosophila melanogaster)
Dmel\CG17752 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG7333 [plasma membrane]
(Drosophila melanogaster)
Orct2 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG4465 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG14857 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG4462 [plasma membrane]
(Drosophila melanogaster)
oct-1 [plasma membrane]
(Caenorhabditis elegans)
Slc22a16 [plasma membrane]
(Mus musculus)
Slc22a16 [plasma membrane]
(Rattus norvegicus)
Dmel\CG7084 [plasma membrane]
(Drosophila melanogaster)
SLC22A16 [plasma membrane]
(Bos taurus)
SLC22A16 [plasma membrane]
(Caenorhabditis elegans)
SLC22A16 [plasma membrane]
(Canis familiaris)
SLC22A16 [plasma membrane]
(Gallus gallus)
SLC22A16 [plasma membrane]
(Sus scrofa)
Balat [plasma membrane]
(Drosophila melanogaster)
Dmel\CG14856 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG6231 [plasma membrane]
(Drosophila melanogaster)
SLC22A [plasma membrane]
(Drosophila melanogaster)
Homologues of SLC22A16 [plasma membrane]
(Caenorhabditis elegans)
Homologues of SLC22A16 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG17751 [plasma membrane]
(Drosophila melanogaster)
slc22a16 [plasma membrane]
(Danio rerio)
slc22a16 [plasma membrane]
(Xenopus tropicalis)
Dmel\CG7458 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG4459 [plasma membrane]
(Drosophila melanogaster)
Cross References
RefSeq
NP_149116.2
,
XP_011534507.1
Guide to Pharmacology - Targets
1024
OpenTargets
ENSG00000004809
GeneCards
Q86VW1
HPA
ENSG00000004809-SLC22A16
Ensembl
ENSP00000357915
,
ENST00000368919
,
ENST00000330550
,
ENSG00000004809
,
ENSP00000328583
ZINC target
Q86VW1
PRO
Q86VW1
Pharos - Targets
Q86VW1
HMDB Protein
HMDBP02811
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BRQ6 CHCHD6
1
CHCHD6 (MIC25) [mitochondrial inner membrane]
(R-HSA-8949568)
0.527
2
UniProt:Q99808 SLC29A1
1
SLC29A1 [plasma membrane]
(R-HSA-54335)
0.527
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text