Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
SLC22A7 [plasma membrane]
Stable Identifier
R-HSA-561082
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
OAT2, Solute carrier family 22 member 7, S22A7_HUMAN
Locations in the PathwayBrowser
Expand all
Drug ADME (Homo sapiens)
Aspirin ADME (Homo sapiens)
SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes (Homo sapiens)
SLC22A7 [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
Organic cation/anion/zwitterion transport (Homo sapiens)
Organic anion transport (Homo sapiens)
OAT1-3 transport organic anions with antiport of dicarboxylic acids (Homo sapiens)
OAT1-3 [plasma membrane] (Homo sapiens)
SLC22A7 [plasma membrane] (Homo sapiens)
OAT2 and OAT4 mediate transport of sulphate conjugates (Homo sapiens)
OAT2/4 [plasma membrane] (Homo sapiens)
SLC22A7 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y694 SLC22A7
Gene Names
SLC22A7, NLT, OAT2
Chain
chain:1-548
Reference Genes
BioGPS Gene:10864 SLC22A7
COSMIC (genes):SLC22A7 SLC22A7
CTD Gene:10864 SLC22A7
dbSNP Gene:10864 SLC22A7
ENSEMBL:ENSG00000137204 SLC22A7
HGNC:10971 SLC22A7
KEGG:hsa:10864 SLC22A7
Monarch:10864 SLC22A7
NCBI Gene:10864 SLC22A7
OMIM:604995 SLC22A7
UCSC:Q9Y694 SLC22A7
Reference Transcript
RefSeq:NM_153320.2 SLC22A7
RefSeq:NM_006672.3 SLC22A7
Other Identifiers
10864
11724371_at
11747887_a_at
11749043_a_at
11761463_x_at
1555553_3p_a_at
1555553_PM_a_at
1555553_a_at
17008950
220554_PM_at
220554_at
221661_PM_at
221661_at
221662_PM_s_at
221662_s_at
231398_PM_at
231398_at
2907888
2907889
2907890
2907891
2907892
2907893
2907894
2907895
2907896
2907897
2907898
2907899
2907900
2907901
2907903
2907904
2907905
2907906
2907907
2907909
2907910
2907911
2907912
2907913
2907914
62538_at
8119782
A_14_P123299
A_23_P93213
A_23_P93217
A_24_P243560
GE54782
GE62502
GO:0005215
GO:0005515
GO:0005737
GO:0005829
GO:0005886
GO:0006805
GO:0006811
GO:0008514
GO:0009925
GO:0015132
GO:0015139
GO:0015347
GO:0015711
GO:0015732
GO:0015742
GO:0016020
GO:0016323
GO:0016324
GO:0022857
GO:0055085
HMNXSV003018033
HMNXSV003041864
Hs.6858.0.A1_3p_at
Hs2.251395.4.S1_3p_at
Hs2.251395.4.S1_3p_s_at
ILMN_1706615
ILMN_1797391
ILMN_2353117
PH_hs_0013302
TC06000599.hg
g12003292_3p_at
g5730048_3p_at
Participates
as a member of
OAT2/4 [plasma membrane] (Homo sapiens)
OAT1-3 [plasma membrane] (Homo sapiens)
Inferred To
Orct [plasma membrane]
(Drosophila melanogaster)
Dmel\CG16727 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG14855 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG4630 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG7342 [plasma membrane]
(Drosophila melanogaster)
pes-23 [plasma membrane]
(Caenorhabditis elegans)
Homologues of SLC22A7 [plasma membrane]
(Caenorhabditis elegans)
Homologues of SLC22A7 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG10486 [plasma membrane]
(Drosophila melanogaster)
slc22a7a [plasma membrane]
(Danio rerio)
Dmel\CG6356 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG5592 [plasma membrane]
(Drosophila melanogaster)
CG6596 [plasma membrane]
(Drosophila melanogaster)
CT19169 [plasma membrane]
(Drosophila melanogaster)
CarT [plasma membrane]
(Drosophila melanogaster)
oct-2 [plasma membrane]
(Caenorhabditis elegans)
suex-2 [plasma membrane]
(Caenorhabditis elegans)
CG31530-RA [plasma membrane]
(Drosophila melanogaster)
CG8654-RA [plasma membrane]
(Drosophila melanogaster)
Dmel\CG17752 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG7333 [plasma membrane]
(Drosophila melanogaster)
Orct2 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG4465 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG14857 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG4462 [plasma membrane]
(Drosophila melanogaster)
oct-1 [plasma membrane]
(Caenorhabditis elegans)
Dmel\CG7084 [plasma membrane]
(Drosophila melanogaster)
Balat [plasma membrane]
(Drosophila melanogaster)
Dmel\CG14856 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG6231 [plasma membrane]
(Drosophila melanogaster)
SLC22A [plasma membrane]
(Drosophila melanogaster)
Dmel\CG17751 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG7458 [plasma membrane]
(Drosophila melanogaster)
SLC22A7 [plasma membrane]
(Bos taurus)
SLC22A7 [plasma membrane]
(Caenorhabditis elegans)
SLC22A7 [plasma membrane]
(Gallus gallus)
SLC22A7 [plasma membrane]
(Sus scrofa)
Slc22a7 [plasma membrane]
(Mus musculus)
Slc22a7 [plasma membrane]
(Rattus norvegicus)
Dmel\CG4459 [plasma membrane]
(Drosophila melanogaster)
Cross References
Guide to Pharmacology - Targets
1026
ENSEMBL
ENSP00000361666
,
ENSP00000361655
,
ENST00000372589
,
ENST00000372585
,
ENST00000372574
,
ENSP00000361670
,
ENSG00000137204
OpenTargets
ENSG00000137204
GeneCards
SLC22A7
HPA
ENSG00000137204-SLC22A7
ZINC - Substances
S22A7_HUMAN
ZINC target
Q9Y694
PRO
Q9Y694
Pharos - Targets
Q9Y694
GlyGen
Q9Y694
ZINC - Predictions - Purchasable
S22A7_HUMAN
HMDB Protein
HMDBP09068
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text