Organic anion transport

Stable Identifier
R-HSA-561048
Type
Pathway
Species
Homo sapiens
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Organic anion transporters (OATs) mediate the renal absorption and excretion of a broad range of endogenous substrates and anionic drugs such as diuretics and NSAIDs. Five members belong to these polyspecific transporters (OAT1-4 and URAT1) and are predominantly expressed in the kidney (Koepsell H and Endou H, 2004; Rizwan AN and Burckhardt G, 2007; Ahn SY and Bhatnagar V, 2008).

Literature References
PubMed ID Title Journal Year
18695391 Update on the molecular physiology of organic anion transporters

Bhatnagar, V, Ahn, SY

Curr Opin Nephrol Hypertens 2008
17245646 Organic anion transporters of the SLC22 family: biopharmaceutical, physiological, and pathological roles

Rizwan, AN, Burckhardt, G

Pharm Res 2007
12883891 The SLC22 drug transporter family

Koepsell, H, Endou, H

Pflugers Arch 2004
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