Reactome | GPR161 [ciliary membrane]

GPR161 [ciliary membrane]

Stable Identifier

R-HSA-5610373

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

ciliary membrane

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Locations in the PathwayBrowser for interactor UniProt:Q8TBA6 GOLGA5

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External Reference Information

External Reference

UniProt:Q8N6U8 GPR161

Gene Names

GPR161

Chain

chain:1-529

Reference Genes

BioGPS Gene:23432 GPR161

COSMIC (genes):GPR161 GPR161

CTD Gene:23432 GPR161

dbSNP Gene:23432 GPR161

ENSEMBL:ENSG00000143147 GPR161

ENSEMBL_homo_sapiens_GENE:ENSG00000143147.15 GPR161

HGNC:23694 GPR161

KEGG Gene (Homo sapiens):23432 GPR161

Monarch:23432 GPR161

NCBI Gene:23432 GPR161

OMIM:612250 GPR161

UCSC:Q8N6U8 GPR161

Reference Transcript

Other Identifiers

11742775_a_at

11742776_s_at

11749295_a_at

16696073

206971_PM_at

206971_at

206972_PM_s_at

206972_s_at

214104_PM_at

214104_at

230369_PM_at

230369_at

232350_3p_x_at

232350_PM_x_at

232350_x_at

23432

235961_PM_at

235961_at

2442913

2442914

2442915

2442916

2442917

2442918

2442919

2442920

2442921

2442922

2442924

2442931

2442932

2442939

2442946

2442947

2442948

2442949

2442952

2442957

2442958

2442960

2442961

2442962

2442963

2442964

2442965

2442966

40300_g_at

40301_at

48259_at

55977_at

77927_i_at

77929_r_at

7922108

A_23_P103532

A_23_P303455

A_23_P354314

A_32_P497742

GE81746

GO:0004930

GO:0005515

GO:0005768

GO:0005886

GO:0005929

GO:0007165

GO:0007186

GO:0007189

GO:0016020

GO:0023052

GO:0030666

GO:0031410

GO:0042995

GO:0043005

GO:0043226

GO:0048856

GO:0055037

GO:0060089

GO:0060170

GO:0097386

GO:1901621

HMNXSV003049054

Hs.21606.0.A1_3p_at

Hs.271809.0.S1_3p_x_at

Hs.301642.1.S1_3p_at

Hs.85893.0.A1_3p_at

ILMN_1658586

ILMN_1773940

PH_hs_0023354

PH_hs_0039137

TC01005921.hg

g6677700_3p_a_at

g6677700_3p_x_at

Participates

as an input of

as a component of

GPR161:IFT-A:TULP3 [cilium] (Homo sapiens)

Other forms of this molecule

GPR161 [endocytic vesicle membrane]

Inferred To

gpr161 [ciliary membrane] (Danio rerio)

gpr161 [ciliary membrane] (Xenopus tropicalis)

GPR161 [ciliary membrane] (Bos taurus)

GPR161 [ciliary membrane] (Canis familiaris)

GPR161 [ciliary membrane] (Gallus gallus)

GPR161 [ciliary membrane] (Sus scrofa)

Gpr161 [ciliary membrane] (Mus musculus)

Gpr161 [ciliary membrane] (Rattus norvegicus)

Cross References

RefSeq

XP_016856348.1, XP_011507678.1, NP_001254542.1, NP_722561.1, XP_016856351.1, XP_011507677.1, XP_005245113.1, NP_001254543.1, XP_016856350.1, XP_005245114.1, XP_005245112.1, XP_016856349.1, NP_001254539.1, NP_001254541.1, XP_011507679.1, XP_011507680.1, NP_001254538.1

Guide to Pharmacology - Targets

141

OpenTargets

ENSG00000143147

HPA

ENSG00000143147-GPR161

GeneCards

Q8N6U8

Ensembl

ENST00000537209, ENSP00000356809, ENST00000546300, ENSP00000506967, ENST00000367838, ENSP00000437576, ENSG00000143147, ENST00000367836, ENST00000367835, ENSP00000441039, ENSP00000444348, ENSP00000356810, ENSP00000356812, ENST00000539777, ENST00000682931

PRO

Q8N6U8

Pharos - Targets

Q8N6U8

Orphanet

23218

PDB

8SMV, 8KH4

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P17612 PRKACA	4	PRKACA [mitochondrial matrix] (R-HSA-9838291) PRKACA [ciliary base] (R-HSA-5610402) PRKACA [nucleoplasm] (R-HSA-111936) PRKACA [cytosol] (R-HSA-57844)	0.643	4
UniProt:P52803 EFNA5	3	EFNA5 (21-?) N-ter [extracellular region] (R-HSA-3928456) EFNA5 (?-203) C-ter [plasma membrane] (R-HSA-3928431) EFNA5 [plasma membrane] (R-HSA-2682331)	0.556	3
UniProt:O75841 UPK1B			0.556	3
UniProt:Q8N6F1-2 CLDN19			0.556	3
UniProt:P21964 COMT	2	COMT [plasma membrane] (R-HSA-379386) COMT [cytosol] (R-HSA-175974)	0.556	3
UniProt:Q9BRI3 SLC30A2	2	SLC30A2 [endosome membrane] (R-HSA-435363) SLC30A2 [synaptic vesicle membrane] (R-HSA-4084714)	0.556	3
UniProt:Q8TBA6 GOLGA5	2	GOLGA5 [transport vesicle] (R-HSA-8847517) GOLGA5 [Golgi membrane] (R-HSA-8847514)	0.527	2
UniProt:P31321 PRKAR1B	2	PRKAR1B [cytosol] (R-HSA-57838) PRKAR1B [ciliary base] (R-HSA-5610409)	0.527	4
UniProt:P22694 PRKACB	3	PRKACB [ciliary base] (R-HSA-5610404) PRKACB [cytosol] (R-HSA-57846) PRKACB [nucleoplasm] (R-HSA-111937)	0.527	3
UniProt:O75317 USP12	1	USP12 [nucleoplasm] (R-HSA-5696907)	0.527	2
UniProt:P22612 PRKACG	3	PRKACG [ciliary base] (R-HSA-5610405) PRKACG [cytosol] (R-HSA-57848) PRKACG [nucleoplasm] (R-HSA-111938)	0.527	3
UniProt:P10644 PRKAR1A	4	PRKAR1A(1-183)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9713476) PRKAR1A(1-183)-ALK(1058-1620) fusion [cytosol] (R-HSA-9713471) PRKAR1A [ciliary base] (R-HSA-5610408) PRKAR1A [cytosol] (R-HSA-57836)	0.527	3

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