The Perilipin (PLIN) gene is transcribed to yield mRNA and the mRNA is translated to yield protein. Expression of Perilipin is upregulated during adipogenesis.
The PPARG:RXRA heterodimer bound to fatty acids activates transcription of the Perilipin (PLIN) gene. In mouse the Pparg:Rxra heterodimer binds the promoter of the Perilipin gene (Leftovera et al. 2008).