Expression of Perilipin (PLIN)

Stable Identifier
R-HSA-560493
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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The Perilipin (PLIN) gene is transcribed to yield mRNA and the mRNA is translated to yield protein. Expression of Perilipin is upregulated during adipogenesis.

The PPARG:RXRA heterodimer bound to fatty acids activates transcription of the Perilipin (PLIN) gene. In mouse the Pparg:Rxra heterodimer binds the promoter of the Perilipin gene (Leftovera et al. 2008).

Literature References
PubMed ID Title Journal Year
16380219 Identification of novel PPARgamma target genes in primary human adipocytes

Perera, RJ, Marcusson, EG, Koo, S, Kang, X, Kim, Y, White, N, Dean, NM

Gene 2006
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