Reactome | GCLC mutants [cytosol]

GCLC mutants [cytosol]

Stable Identifier

R-HSA-5602923

Type

Set [DefinedSet]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

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Disease (Homo sapiens)

- Diseases of metabolism (Homo sapiens)
  - Metabolic disorders of biological oxidation enzymes (Homo sapiens)
    - Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) (Homo sapiens)
      - Defective GCLC does not ligate L-Glu to L-Cys (Homo sapiens)
        
        GCLC mutants:GCLM [cytosol] (Homo sapiens)
        
        GCLC mutants [cytosol] (Homo sapiens)

Participants

members

Participant Of

hasComponent

GCLC mutants:GCLM [cytosol]

Disease

Name	Identifier	Synonyms
hemolytic anemia	583	Hemolytic anemias (disorder), Hemolytic anemia (disorder), Hemolytic anemias NOS (disorder), hemolytic anemia, ANEMIA HEMOLYTIC

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