Unknown nuclease cleaves cleaved transposon RNA in 6xMeR-PIWIL2:cleaved transposon RNA:TDRD1:TDRD12:DDX4:ASZ:MOV10L1

Stable Identifier
R-HSA-5601929
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

After the cleaved RNA binds PIWIL2 (HILI in human, homolog of Mili in mouse) the 3' end is trimmed by an unknown nuclease to generate a mature piRNA. The resulting PIWIL2:piRNA complex can then participate in further amplification by the "ping-pong" cycle.

Participants
Participant Of
Inferred From
Authored
Reviewed
Created