Unknown nuclease cleaves cleaved transposon RNA in 6xMeR-PIWIL2:cleaved transposon RNA:TDRD1:TDRD12:DDX4:ASZ:MOV10L1

Stable Identifier
R-HSA-5601929
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Unknown nuclease cleaves cleaved transposon RNA in 6xMeR-PIWIL2:cleaved transposon RNA:TDRD1:TDRD12:DDX4:ASZ:MOV10L1
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After the cleaved RNA binds PIWIL2 (HILI in human, homolog of Mili in mouse) the 3' end is trimmed by an unknown nuclease to generate a mature piRNA. The resulting PIWIL2:piRNA complex can then participate in further amplification by the "ping-pong" cycle.
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Unknown nuclease cleaves cleaved transposon RNA in Asz1:Ddx4:Mov10l1:6xMeR-Piwil2:piRNA:Tdrd1:Tdrd12 (Mus musculus)
Authored
May, B  (2014-06-14)
Reviewed
Saito, K  (2014-10-25)
Created
May, B  (2014-06-15)
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