Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
MeR-PIWIL4 [cytosol]
Stable Identifier
R-HSA-5601903
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Piwi-like protein 4, PIWL4_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
Gene Silencing by RNA (Homo sapiens)
PIWI-interacting RNA (piRNA) biogenesis (Homo sapiens)
Complexed PIWIL4 binds cleaved transposon RNA (Homo sapiens)
MeR-PIWIL4:TDRD9:MAEL:TDRKH [cytosol] (Homo sapiens)
MeR-PIWIL4 [cytosol] (Homo sapiens)
MeR-PIWIL4:cleaved transposon RNA:TDRD9:MAEL:TDRKH [cytosol] (Homo sapiens)
MeR-PIWIL4:cleaved transposon RNA [cytosol] (Homo sapiens)
MeR-PIWIL4 [cytosol] (Homo sapiens)
HENMT1 methylates 2' hydroxyl at 3' end of piRNA in MeR-PIWIL4:piRNA:TDRD9:MAEL:TDRKH (Homo sapiens)
MeR-PIWIL4:2'-O-methyl-piRNA:TDRD9:MAEL:TDRKH [cytosol] (Homo sapiens)
MeR-PIWIL4:2'-O-methyl-piRNA [cytosol] (Homo sapiens)
MeR-PIWIL4 [cytosol] (Homo sapiens)
MeR-PIWIL4:piRNA:TDRD9:MAEL:TDRKH [cytosol] (Homo sapiens)
MeR-PIWIL4:piRNA [cytosol] (Homo sapiens)
MeR-PIWIL4 [cytosol] (Homo sapiens)
MeR-PIWIL4:2'-O-methyl-piRNA:TDRD9:MAEL:TDRKH dissociates and MeR-PIWIL4:2'-O-methylpiRNA, TDRD9, MAEL translocate from cytosol to nucleus in an unknown association and order of events (Homo sapiens)
MeR-PIWIL4:2'-O-methyl-piRNA:TDRD9:MAEL:TDRKH [cytosol] (Homo sapiens)
MeR-PIWIL4:2'-O-methyl-piRNA [cytosol] (Homo sapiens)
MeR-PIWIL4 [cytosol] (Homo sapiens)
Unknown nuclease cleaves cleaved transposon RNA bound in MeR-PIWIL4:cleaved transposon RNA:TDRD9:MAEL:TDRKH (Homo sapiens)
MeR-PIWIL4:cleaved transposon RNA:TDRD9:MAEL:TDRKH [cytosol] (Homo sapiens)
MeR-PIWIL4:cleaved transposon RNA [cytosol] (Homo sapiens)
MeR-PIWIL4 [cytosol] (Homo sapiens)
MeR-PIWIL4:piRNA:TDRD9:MAEL:TDRKH [cytosol] (Homo sapiens)
MeR-PIWIL4:piRNA [cytosol] (Homo sapiens)
MeR-PIWIL4 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q7Z3Z4 PIWIL4
Gene Names
PIWIL4, HIWI2, PIWI
Chain
chain:1-852
Reference Genes
BioGPS Gene:143689 PIWIL4
COSMIC (genes):PIWIL4 PIWIL4
CTD Gene:143689 PIWIL4
dbSNP Gene:143689 PIWIL4
ENSEMBL:ENSG00000134627 PIWIL4
ENSEMBL_homo_sapiens_GENE:ENSG00000134627.12 PIWIL4
HGNC:18444 PIWIL4
KEGG Gene (Homo sapiens):143689 PIWIL4
Monarch:143689 PIWIL4
NCBI Gene:143689 PIWIL4
OMIM:610315 PIWIL4
UCSC:Q7Z3Z4 PIWIL4
Reference Transcript
RefSeq:NM_152431.2 PIWIL4
Other Identifiers
11756909_a_at
143689
16730215
230480_PM_at
230480_at
3345150
3345159
3345160
3345161
3345163
3345164
3345165
3345166
3345168
3345169
3345170
3345171
3345172
3345173
3345174
3345175
3345176
3345177
3345178
3345179
3345181
3345182
3345183
3345185
3345186
3345187
3345188
3345189
53580_at
7943240
A_14_P102931
A_14_P117024
A_23_P427760
A_24_P295609
GE496461
GE79641
GO:0003676
GO:0003723
GO:0003824
GO:0004521
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0006417
GO:0007283
GO:0010669
GO:0016787
GO:0022414
GO:0030154
GO:0031047
GO:0034584
GO:0043186
GO:0043226
GO:0051321
GO:0071547
GO:0140098
GO:0140965
GO:0141005
GO:0141007
HMNXSV003030523
Hs.58248.0.A1_3p_at
ILMN_1769606
ILMN_2147078
PH_hs_0003745
TC11000921.hg
Participates
as a component of
MeR-PIWIL4:TDRD9:MAEL:TDRKH [cytosol] (Homo sapiens)
MeR-PIWIL4:cleaved transposon RNA [cytosol] (Homo sapiens)
MeR-PIWIL4:piRNA [cytosol] (Homo sapiens)
MeR-PIWIL4:2'-O-methyl-piRNA [cytosol] (Homo sapiens)
Other forms of this molecule
MeR-PIWIL4 [nucleoplasm]
Inferred From
MeR-Piwil4 [cytosol]
(Mus musculus)
Modified Residues
Name
symmetric dimethyl-L-arginine at unknown position
PsiMod Name
symmetric dimethyl-L-arginine
PsiMod Definition
A protein modification that effectively converts an L-arginine residue to symmetric dimethylarginine, N(omega),N'(omega)-dimethyl-L-arginine.
Cross References
RefSeq
NP_689644.2
OpenTargets
ENSG00000134627
HPA
ENSG00000134627-PIWIL4
GeneCards
Q7Z3Z4
Ensembl
ENST00000299001
,
ENSG00000134627
,
ENSP00000299001
,
ENSP00000444575
,
ENSP00000413838
,
ENST00000446230
,
ENST00000543336
PRO
Q7Z3Z4
Pharos - Targets
Q7Z3Z4
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text