Reactome | 4xMeR-PIWIL1 [cytosol]

4xMeR-PIWIL1 [cytosol]

Stable Identifier

R-HSA-5601891

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Piwi-like protein 1, PIWL1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q96J94 PIWIL1

Gene Names

PIWIL1, HIWI

Chain

chain:1-861

Reference Genes

BioGPS Gene:9271 PIWIL1

COSMIC (genes):PIWIL1 PIWIL1

CTD Gene:9271 PIWIL1

dbSNP Gene:9271 PIWIL1

ENSEMBL:ENSG00000125207 PIWIL1

ENSEMBL_homo_sapiens_GENE:ENSG00000125207.7 PIWIL1

ENSEMBL_homo_sapiens_GENE:ENSG00000275051.2 PIWIL1

HGNC:9007 PIWIL1

KEGG Gene (Homo sapiens):9271 PIWIL1

Monarch:9271 PIWIL1

NCBI Gene:9271 PIWIL1

OMIM:605571 PIWIL1

UCSC:Q96J94 PIWIL1

Reference Transcript

Other Identifiers

11728487_at

16759159

214868_PM_at

214868_at

3437831

3437832

3437837

3437838

3437841

3437842

3437843

3437846

3437848

3437849

3437850

3437853

3437855

3437856

3437857

3437858

3437860

3437861

3437862

3437863

3437864

3437865

3437869

3437871

3437872

3437873

3437874

35901_at

76330_r_at

7959856

9271

A_14_P109064

A_14_P200785

A_23_P116741

GE472658

GO:0003676

GO:0003723

GO:0003727

GO:0003729

GO:0003824

GO:0004518

GO:0004519

GO:0004521

GO:0005515

GO:0005634

GO:0005737

GO:0006325

GO:0006417

GO:0007283

GO:0007286

GO:0016787

GO:0019901

GO:0022414

GO:0030154

GO:0031047

GO:0033391

GO:0034584

GO:0035092

GO:0043186

GO:0043226

GO:0046872

GO:0048856

GO:0051321

GO:0061980

GO:0097433

GO:0140098

GO:0140262

GO:0140990

GO:0141006

GO:1905538

HMNXSV003024461

Hs.194712.0.S1_3p_at

Hs.194712.0.S1_3p_x_at

ILMN_1701220

PH_hs_0024659

TC12001034.hg

Participates

as a component of

Inferred From

4xMeR-Piwil1 [cytosol] (Mus musculus)

Modified Residues

Name

symmetric dimethyl-L-arginine at 14

Coordinate

PsiMod Name

symmetric dimethyl-L-arginine

PsiMod Definition

A protein modification that effectively converts an L-arginine residue to symmetric dimethylarginine, N(omega),N'(omega)-dimethyl-L-arginine.

Name

omega-N-methyl-L-arginine at 49

Coordinate

PsiMod Name

omega-N-methyl-L-arginine

PsiMod Definition

A protein modification that effectively converts an L-arginine residue to N(omega)-methyl-L-arginine.

Name

omega-N-methyl-L-arginine at 53

Coordinate

PsiMod Name

omega-N-methyl-L-arginine

PsiMod Definition

A protein modification that effectively converts an L-arginine residue to N(omega)-methyl-L-arginine.

Name

omega-N-methyl-L-arginine at 370

Coordinate

370

PsiMod Name

omega-N-methyl-L-arginine

PsiMod Definition

A protein modification that effectively converts an L-arginine residue to N(omega)-methyl-L-arginine.

Cross References

RefSeq

NP_004755.2, XP_011537304.1, XP_011537306.1, XP_011537305.1, NP_001177900.1

OpenTargets

ENSG00000125207

HPA

ENSG00000125207-PIWIL1

GeneCards

Q96J94

Ensembl

ENSP00000481042, ENST00000245255, ENST00000632888, ENST00000613226, ENSP00000245255, ENSG00000125207, ENSG00000275051, ENSP00000487688

PRO

Q96J94

Pharos - Targets

Q96J94

PDB

3O6E, 6PI7, 3O7V, 3O3I, 2L5D, 2L5C

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:Q9UPY3 DICER1	1	DICER1 [cytosol] (R-HSA-203820)	0.499	2