Reactome | GPD1 [cytosol]

GPD1 [cytosol]

Stable Identifier

R-HSA-55875

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Glycerol-3-phosphate dehydrogenase (NAD+), cytoplasmic , GPD-C, GPDH-C

Locations in the PathwayBrowser

Expand all

Metabolism (Homo sapiens)

- Metabolism of lipids (Homo sapiens)
  - Phospholipid metabolism (Homo sapiens)
    - Glycerophospholipid biosynthesis (Homo sapiens)
      - Synthesis of PA (Homo sapiens)
        
        DHAP is converted to G3P by GPD1/GPD1L (Homo sapiens)
        
        GPD1/GPD1L homodimer [cytosol] (Homo sapiens)
        
        GPD1 dimer [cytosol] (Homo sapiens)
        
        GPD1 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:P21695 GPD1

Gene Names

GPD1

Chain

chain:1-349

Reference Genes

BioGPS Gene:2819 GPD1

COSMIC (genes):GPD1 GPD1

CTD Gene:2819 GPD1

dbSNP Gene:2819 GPD1

ENSEMBL:ENSG00000167588 GPD1

HGNC:4455 GPD1

KEGG:hsa:2819 GPD1

Monarch:2819 GPD1

NCBI Gene:2819 GPD1

OMIM:138420 GPD1

UCSC:P21695 GPD1

Reference Transcript

Other Identifiers

11720472_a_at

11720473_at

11748917_a_at

11761423_x_at

1563034_PM_at

1563034_at

1563035_3p_x_at

1563035_PM_x_at

1563035_x_at

16751048

204997_PM_at

204997_at

213706_PM_at

213706_at

2819

33902_at

3414420

3414421

3414422

3414423

3414424

3414425

3414426

3414427

3414428

3414429

3414430

3414431

3414432

3414433

3414434

3414435

3414436

3414437

3414438

3414439

3414441

3414442

3414443

3414444

3414445

3414446

7955348

A_14_P135604

A_23_P162660

A_23_P204736

GE81485

GO:0003824

GO:0004368

GO:0005515

GO:0005737

GO:0005829

GO:0005975

GO:0006072

GO:0006094

GO:0006116

GO:0006127

GO:0006629

GO:0006734

GO:0009331

GO:0016491

GO:0016616

GO:0042803

GO:0043226

GO:0045821

GO:0046168

GO:0046486

GO:0047952

GO:0051287

GO:0055086

GO:0070062

GO:0071320

GO:0071356

GO:0141152

GO:1901135

HMNXSV003004166

Hs.9739.1.A1_3p_at

Hs2.350554.1.S1_3p_x_at

ILMN_1764175

PH_hs_0023929

Participates

as a component of

GPD1 dimer [cytosol] (Homo sapiens)

Inferred To

Homologues of GPD1 [cytosol] (Caenorhabditis elegans)

Homologues of GPD1 [cytosol] (Drosophila melanogaster)

Homologues of GPD1 [cytosol] (Plasmodium falciparum)

Homologues of GPD1 [cytosol] (Saccharomyces cerevisiae)

Homologues of GPD1 [cytosol] (Schizosaccharomyces pombe)

Gpdh3 [cytosol] (Drosophila melanogaster)

GPD1 [cytosol] (Bos taurus)

GPD1 [cytosol] (Caenorhabditis elegans)

GPD1 [cytosol] (Canis familiaris)

GPD1 [cytosol] (Danio rerio)

GPD1 [cytosol] (Drosophila melanogaster)

GPD1 [cytosol] (Mus musculus)

GPD1 [cytosol] (Plasmodium falciparum)

GPD1 [cytosol] (Rattus norvegicus)

GPD1 [cytosol] (Saccharomyces cerevisiae)

GPD1 [cytosol] (Schizosaccharomyces pombe)

GPD1 [cytosol] (Sus scrofa)

GPD1 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_005267.2, NP_001244128.1

ENSEMBL

ENST00000548814, ENSP00000446768, ENSP00000301149, ENST00000301149

OpenTargets

ENSG00000167588

HPA

ENSG00000167588-GPD1

PRO

P21695

Pharos - Targets

P21695

Orphanet

GPD1

HMDB Protein

HMDBP00837

PDB

1WPQ, 6E90, 1X0X, 6PYP, 6E8Z, 6E8Y, 1X0V

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