Reactome | MED9 [nucleoplasm]

MED9 [nucleoplasm]

Stable Identifier

R-HSA-556804

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Mediator of RNA polymerase II transcription subunit 9, MED9_HUMAN

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - Respiratory Syncytial Virus Infection Pathway (Homo sapiens)
      - RSV-host interactions (Homo sapiens)
        
        NS1 (1C) binds to Mediator complex (Homo sapiens)
        
        Mediator Complex (consensus) [nucleoplasm] (Homo sapiens)
        
        MED9 [nucleoplasm] (Homo sapiens)
        
        Mediator:NS1 [nucleoplasm] (Homo sapiens)
        
        Mediator Complex (consensus) [nucleoplasm] (Homo sapiens)
        
        MED9 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9NWA0 MED9

Gene Names

MED9, MED25

Chain

initiator methionine:, chain:2-146

Reference Genes

BioGPS Gene:55090 MED9

COSMIC (genes):MED25 MED9

COSMIC (genes):MED9 MED9

CTD Gene:55090 MED9

dbSNP Gene:55090 MED9

ENSEMBL:ENSG00000141026 MED9

HGNC:25487 MED9

KEGG:hsa:55090 MED9

Monarch:55090 MED9

NCBI Gene:55090 MED9

OMIM:609878 MED9

UCSC:Q9NWA0 MED9

Reference Transcript

RefSeq:NM_018019.2 MED9

Other Identifiers

11718668_at

11718669_x_at

11718670_at

16831614

218372_PM_at

218372_at

3712597

3712598

3712599

3712600

3712604

3712606

3712607

3712608

3712609

3712611

45145_at

49187_at

55090

63149_at

8005260

A_14_P108023

A_23_P66402

A_24_P8267

GE513871

GE87617

GO:0003712

GO:0005515

GO:0005634

GO:0005654

GO:0006355

GO:0006357

GO:0016592

GO:0032968

GO:0043226

GO:0051123

GO:0060090

GO:0060261

GO:0065003

GO:0070847

GO:0140110

HMNXSV003009289

ILMN_1794108

PH_hs_0012814

TC17000199.hg

g8922272_3p_at

Participates

as a component of

Mediator Complex (consensus) [nucleoplasm] (Homo sapiens)

Cross References

OpenTargets

ENSG00000141026

ENSEMBL

ENSP00000268711, ENST00000268711, ENSG00000141026

HPA

ENSG00000141026-MED9

GeneCards

MED9

PRO

Q9NWA0

Pharos - Targets

Q9NWA0

GlyGen

Q9NWA0

PDB

8GXS, 7LBM, 7NVR, 8GXQ, 7ENJ, 7ENA, 7ENC, 8TQW, 8TRH, 8T9D, 7EMF

Interactors (23)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P49336 CDK8	1	CDK8 [nucleoplasm] (R-HSA-212440)	0.899	11
UniProt:Q9NPJ6 MED4	1	MED4 [nucleoplasm] (R-HSA-350263)	0.895	17
UniProt:Q15648 MED1	1	MED1 [nucleoplasm] (R-HSA-212445)	0.837	9
UniProt:O43513 MED7	1	MED7 [nucleoplasm] (R-HSA-212430)	0.837	7
UniProt:Q9BTT4 MED10	1	MED10 [nucleoplasm] (R-HSA-212410)	0.825	9
UniProt:Q9Y3C7 MED31	1	MED31 [nucleoplasm] (R-HSA-212429)	0.725	5
UniProt:O95402 MED26	1	MED26 [nucleoplasm] (R-HSA-556783)	0.725	6
UniProt:Q9H944 MED20	1	MED20 [nucleoplasm] (R-HSA-212428)	0.725	6
UniProt:O75448 MED24	1	MED24 [nucleoplasm] (R-HSA-212331)	0.725	5
UniProt:Q9NVC6 MED17	1	MED17 [nucleoplasm] (R-HSA-212401)	0.725	6
UniProt:Q96HR3 MED30	1	MED30 [nucleoplasm] (R-HSA-212398)	0.725	4
UniProt:Q93074 MED12	1	MED12 [nucleoplasm] (R-HSA-212343)	0.725	4
UniProt:Q96G25 MED8	1	MED8 [nucleoplasm] (R-HSA-556784)	0.643	5
UniProt:Q9UHV7 MED13	1	MED13 [nucleoplasm] (R-HSA-212391)	0.643	3
UniProt:P19388 POLR2E	2	POLR2E [cytosol] (R-HSA-1964438) POLR2E [nucleoplasm] (R-HSA-83713)	0.643	3
UniProt:O60244 MED14	1	MED14 [nucleoplasm] (R-HSA-212441)	0.643	4
UniProt:Q9Y2X0 MED16	1	MED16 [nucleoplasm] (R-HSA-556802)	0.643	3
UniProt:Q6P2C8 MED27	1	MED27 [nucleoplasm] (R-HSA-556761)	0.643	4
UniProt:Q71SY5 MED25	1	MED25 [nucleoplasm] (R-HSA-212414)	0.643	3
UniProt:O75586 MED6	1	MED6 [nucleoplasm] (R-HSA-212359)	0.643	4
UniProt:Q9ULK4 MED23	1	MED23 [nucleoplasm] (R-HSA-556823)	0.615	3
UniProt:Q96RN5 MED15	1	MED15 [nucleoplasm] (R-HSA-556827)	0.527	2
UniProt:P24863 CCNC	1	CCNC [nucleoplasm] (R-HSA-212418)	0.527	3